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==Overview==
==Overview==

Revision as of 16:32, 30 June 2017

Pheochromocytoma Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]Mohammed Abdelwahed M.D[3]

Overview

The incidence of pheochromocytoma ranges from a low of 0.2 per 100,000 persons to a high of 0.8 per 100,000 persons. The average age at diagnosis is 24.9 years in hereditary cases and 43.9 years in sporadic cases with men and women equally affected.[1]

Epidemiology and Demographics

Incidence

In the USA, the incidence of pheochromocytoma ranges from a low of 0.2 per 100,000 persons to a high of 0.8 per 100,000 persons [1]  and 500 to 1600 cases in the United States per year [2] but autopsy series discovered numbers higher that those of prevalence rates. 10% of pheochromocytomas are discovered by chance. null 22

Pheochromocytomas occur all races but less in black. Approximately 10% occur in children. Fifty percent of pheochromocytomas in children are solitary intra-adrenal lesions, 25% are present bilaterally, and 25% are extra-adrenal.

Most catecholamine-secreting tumors are sporadic. However, 30% of patients got the tumor as a part of familial disease, the catecholamine-secreting tumors are more likely to be bilateral.

Age

The peak incidence of pheochromocytoma occurs in third to fifth decades of life; the average age at diagnosis is 24.9 years in hereditary cases and 43.9 years in sporadic cases.[1]. Hereditary tumors present at a younger age than sporadic.

Gender

Men and women are equally affected by pheochromocytoma.[1]

References

  1. 1.0 1.1 1.2 1.3 National Cancer Institute. Physician Data Query Database 2015. National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_25_toc
  2. Chen H, Sippel RS, O'Dorisio MS, Vinik AI, Lloyd RV, Pacak K; et al. (2010). "The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer". Pancreas. 39 (6): 775–83. doi:10.1097/MPA.0b013e3181ebb4f0. PMC 3419007. PMID 20664475.


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