Patent ductus arteriosus causes: Difference between revisions
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==Causes== | ==Causes== | ||
*Genetic factors | ===Common Causes=== | ||
*[[ | Common causes of patent ductus arteriosus may include: | ||
*[[Fetal alcohol syndrome]] | *Genetic factors<ref name="pmid8326495">{{cite journal| author=Davidson HR| title=A large family with patent ductus arteriosus and unusual face. | journal=J Med Genet | year= 1993 | volume= 30 | issue= 6 | pages= 503-5 | pmid=8326495 | doi= | pmc=PMC1016426 | url= }} </ref> | ||
*Maternal [[ | **PDA has is highly familial. It is shown that with the effect of environmental elements. | ||
**Studies shown the [[inheritance]] is more contributed to [[autosomal dominant]].<ref name="BhandariZhou2009">{{cite journal|last1=Bhandari|first1=V.|last2=Zhou|first2=G.|last3=Bizzarro|first3=M. J.|last4=Buhimschi|first4=C.|last5=Hussain|first5=N.|last6=Gruen|first6=J. R.|last7=Zhang|first7=H.|title=Genetic Contribution to Patent Ductus Arteriosus in the Premature Newborn|journal=PEDIATRICS|volume=123|issue=2|year=2009|pages=669–673|issn=0031-4005|doi=10.1542/peds.2008-1117}}</ref> | |||
*[[Congenital rubella]]<ref name="Mekonnen2017">{{cite journal|last1=Mekonnen|first1=Demeke|title=Clinically confirmed congenital rubella syndrome: the role of echocardiography|journal=Ethiopian Journal of Health Sciences|volume=27|issue=2|year=2017|pages=197|issn=1029-1857|doi=10.4314/ejhs.v27i2.13}}</ref> | |||
*[[Fetal alcohol syndrome]]<ref name="ArishimaYamamoto1993">{{cite journal|last1=Arishima|first1=Kazuyoshi|last2=Yamamoto|first2=Masako|last3=Takizawa|first3=Tatsuya|last4=Sohmiya|first4=Hiroaki|last5=Eguchi|first5=Yasunobu|last6=Shiota|first6=Kohei|title=Effect of Acute Maternal Alcohol Consumption on the Fetal Ductus arteriosus in the Rat|journal=Neonatology|volume=63|issue=1|year=1993|pages=40–43|issn=1661-7800|doi=10.1159/000243906}}</ref> | |||
===Less Common Causes=== | |||
Less common causes of PDA include: | |||
*Maternal [[teratogen]] drug use<ref name="ReeseVeldman2010">{{cite journal|last1=Reese|first1=Jeff|last2=Veldman|first2=Alex|last3=Shah|first3=Lisa|last4=Vucovich|first4=Megan|last5=Cotton|first5=Robert B.|title=Inadvertent Relaxation of the Ductus Arteriosus by Pharmacologic Agents that are Commonly Used in the Neonatal Period|journal=Seminars in Perinatology|volume=34|issue=3|year=2010|pages=222–230|issn=01460005|doi=10.1053/j.semperi.2010.02.007}}</ref>: | |||
**[[Amphetamine]] | **[[Amphetamine]] | ||
**[[Clomifene]] | **[[Clomifene]] | ||
**[[Phenytoin]] | **[[Phenytoin]] | ||
===Causes by Organ System=== | ===Causes by Organ System=== | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| Maternal [[Amphetamine]], [[Clomifene]], [[Phenytoin]], [[Fetal alcohol spectrum disorder|Alcohol]] use | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Environmental''' | | '''Environmental''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| Many underlying co founders in research | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Genetic''' | | '''Genetic''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"|[[Autosomal dominant]] inheritance reported | ||
|- | |- | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Infectious Disease''' | | '''Infectious Disease''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"|[[Congenital rubella syndrome|Congenital rubella]] infection | ||
|- | |- | ||
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Revision as of 16:02, 9 February 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Priyamvada Singh, M.B.B.S. [2], Cafer Zorkun, M.D., Ph.D. [3], Assistant Editor-In-Chief: Kristin Feeney, B.S. [4] Ramyar Ghandriz MD[5]
Overview
Causes of Patent ductus arteriosus is not known. However, increased incidence have been associated with mother's rubella and genetic causes
Causes
Common Causes
Common causes of patent ductus arteriosus may include:
- Genetic factors[1]
- PDA has is highly familial. It is shown that with the effect of environmental elements.
- Studies shown the inheritance is more contributed to autosomal dominant.[2]
- Congenital rubella[3]
- Fetal alcohol syndrome[4]
Less Common Causes
Less common causes of PDA include:
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Maternal Amphetamine, Clomifene, Phenytoin, Alcohol use |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | Many underlying co founders in research |
| Gastroenterologic | No underlying causes |
| Genetic | Autosomal dominant inheritance reported |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | Congenital rubella infection |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
References
- ↑ Davidson HR (1993). "A large family with patent ductus arteriosus and unusual face". J Med Genet. 30 (6): 503–5. PMC 1016426. PMID 8326495.
- ↑ Bhandari, V.; Zhou, G.; Bizzarro, M. J.; Buhimschi, C.; Hussain, N.; Gruen, J. R.; Zhang, H. (2009). "Genetic Contribution to Patent Ductus Arteriosus in the Premature Newborn". PEDIATRICS. 123 (2): 669–673. doi:10.1542/peds.2008-1117. ISSN 0031-4005.
- ↑ Mekonnen, Demeke (2017). "Clinically confirmed congenital rubella syndrome: the role of echocardiography". Ethiopian Journal of Health Sciences. 27 (2): 197. doi:10.4314/ejhs.v27i2.13. ISSN 1029-1857.
- ↑ Arishima, Kazuyoshi; Yamamoto, Masako; Takizawa, Tatsuya; Sohmiya, Hiroaki; Eguchi, Yasunobu; Shiota, Kohei (1993). "Effect of Acute Maternal Alcohol Consumption on the Fetal Ductus arteriosus in the Rat". Neonatology. 63 (1): 40–43. doi:10.1159/000243906. ISSN 1661-7800.
- ↑ Reese, Jeff; Veldman, Alex; Shah, Lisa; Vucovich, Megan; Cotton, Robert B. (2010). "Inadvertent Relaxation of the Ductus Arteriosus by Pharmacologic Agents that are Commonly Used in the Neonatal Period". Seminars in Perinatology. 34 (3): 222–230. doi:10.1053/j.semperi.2010.02.007. ISSN 0146-0005.