Papillary thyroid cancer (patient information): Difference between revisions

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{{Papillary thyroid cancer (patient information)}}
{{Papillary thyroid cancer (patient information)}}
{{CMG}}; {{AE}} {{Ammu}}
{{CMG}}; {{AE}} {{Ammu}}; {{AE}} {{AJL}}


'''For the WikiDoc page for this topic, click [[Papillary thyroid cancer|here]]'''
'''For the WikiDoc page for this topic, click [[Papillary thyroid cancer|here]]'''
==Overview==
==Overview==
Thyroid is a butterfly-shaped gland in the neck which makes hormones to help the body work normally. papillary thyroid cancer is a cancer that starts in the thyroid gland. papillary thyroid cancer doesn't have any early symptoms. With the development of tne cancer, usual symptoms include a [[lump]] that can be felt through the skin on your neck, [[hoarseness]], difficulty swallowing, [[pain]] in the neck and throat and swollen lymph nodes in the neck. Treatments include [[surgery]], [[radiation therapy]], [[chemotherapy]], thyroid hormone therapy or a combination of them.
The [[thyroid gland]], a butterfly-shaped gland in the [[neck]], produces body-regulating hormones. Papillary thyroid cancer starts in the [[thyroid gland]] and manifests without early-stage symptoms. As the [[cancer]] further develops, noticeable [[symptoms]] begin to arise, such as vocal [[hoarseness]], difficulty swallowing, a lump in the [[neck]], which can be felt through the [[skin]], neck or throat [[pain]], and [[swollen lymph nodes]]. Treatment options include [[surgery]], [[radiation therapy]], [[chemotherapy]], and thyroid hormone therapy.


==What are the symptoms of papillary thyroid cancer?==
==What are the symptoms of papillary thyroid cancer?==
Early papillary thyroid cancer does not have any symptoms. As the tumor grows larger, people may notice one or more of the following symptoms:  
While [[patients]] with early papillary thyroid cancer do not present with any [[symptoms]], as the tumor grows larger people may notice one or more of the following [[symptoms]]:  


:*A nodule, [[lump]], or swelling in the neck
*A nodule, [[lump]], or swelling in the [[neck]], which may be perceptible by touch
*Pain in the throat/neck
*Vocal [[hoarseness]]
*[[Difficulty swallowing]]
*Swollen [[lymph nodes]]


==What causes papillary thyroid cancer?==
==What causes papillary thyroid cancer?==
* The exact cause of papillary thyroid cancer is unknown. Certain genetic mutation is suscepted to be the cause of papillary thyroid cancer.
* While the exact cause of papillary thyroid cancer is unknown, certain [[genetic mutations]] are suspected to be associated with the [[disease]].
* People who have had radiation therapy to the neck are at higher risk. Radiation therapy was commonly used in the 1950s to treat enlarged thymus glands, adenoids and tonsils, and skin disorders. People who received radiation therapy as children are at increased risk for developing papillary thyroid cancer.
*People who have had [[radiation therapy]] to the neck area, or as children, are at higher risk for developing papillary thyroid cancer. [[Radiation therapy]] was commonly used in the 1950's to treat [[skin disorders]] and enlarged [[thymus]] gland, [[adenoids]], and [[tonsils]].


==Who is at highest risk?==
==Who is at highest risk?==
Clinical data have suggested that the development of papillary thyroid cancer is related to several factors.
Clinical data have suggested that the development of papillary thyroid cancer is related to various factors, such as:


:*A diet low in iodine: Clinical survey show papillary thyroid cancers are more common in areas where people's diets are low in iodine.
:*A diet low in [[iodine]]: papillary thyroid cancers are more common in regions characterized by iodine-deficient diets.
:*Radiation: Scientists has proven that radiation exposure is a risk factor for papillary thyroid cancer. Such radiation includes medical treatments and radiation fallout from power plant accidents or nuclear weapons.
:*[[Radiation exposure]]
:*Hereditary conditions: Studies show people with certain inherited medical conditions such as Gardner syndrome, Cowden disease, and familial adenomatous polyposis (FAP) are at higher risk of developing papillary thyroid cancer.
:*[[Patients]] over the age of 45-years
:*Gender: Contrary to other cancers, papillary thyroid cancers occur more often in women than in men.
:*Age: Clinical data show that papillary and papillary thyroid cancer are usually found in people between the ages of 20 and 60 years.


==Diagnosis==
==Diagnosis==
Your doctor will perform a physical exam. This may reveal a lump in the thyroid, or swollen lymph nodes in the neck.
Firstly, a doctor will likely preform a physical exam (noting [[swollen lymph nodes]] and lumps in the neck that are perceptible by touch) and review patient medical history. Based upon the [[physical examination]] the patient's self-reported symptoms, the doctor may recommend the following tests:


The following tests may be done:
*[[Laryngoscopy]]
 
*[[Thyroid]] biopsy
* Calcitonin blood test to check for medullary cancer
*[[Thyroid]] scan
* Thyroglobulin blood test to check for papillary or follicular cancer
*[[Ultrasound]] of the [[thyroid]]
* Laryngoscopy
* Thyroid biopsy
* Thyroid scan
* Ultrasound of the thyroid
 
This disease may also affect the results of the following thyroid function tests:
 
* T3
* T4
* TSH


==When to seek urgent medical care?==
==When to seek urgent medical care?==
Call your health care provider if symptoms of thyroid cancer develop.
Call your health care provider if [[symptoms]] of thyroid cancer develop.


==Treatment options==
==Treatment options==
In order to diagnose papillary thyroid cancer, your doctor may suggest you the following tests:
:*Thyroid hormones tests: Thyroid hormones including F3, F4, FF3, FF4 and TSH (thyroid-stimulating hormone) are needed to assess thyroid gland function.
:*Fine needle aspiration [[biopsy]]: The doctor places a thin, hollow needle directly into the nodule to take out cells and repeats twice or three times to receive samples from several areas of the nodule. Then these cells can be checked under a microscope to see whether cancerous or benign.
:*Thyroid gland radioiodine scan: During this test, the doctors put substances with small amounts of radiation into your body and detect the location of the substances. The test can help locate abnormal cells in the body.
:*Computed tomography (CT) scan and biopsy: CT scans are often used to diagnose papillary thyroid cancer. It can help determine the location and size of papillary thyroid cancers and whether they have spread to nearby or distant areas. These are helpful for identifying the stage of the cancer and in determining whether surgery is a good treatment option. CT scans can also be used to guide biopsy and a biopsy sample is usually removed and looked at under a microscope.
:*Magnetic resonance imaging (MRI): An MRI uses magnetic fields but it is a different type of image than what is produced by computed tomography (CT) and produces very detailed images of soft tissues such as the thyroid glands. Like computed tomography (CT), a contrast agent may be injected into a patient’s vein to create a better picture.
:*Positron emission tomography (PET) scan: When doing this test, a small amount of a radioactive medium is injected into your body and absorbed by the organs or tissues. This radioactive substance gives off energy which in turn is used to produce the images. PET can provide more helpful information than either CT or MRI scans. It is useful to see if the cancer has spread to the lymph nodes and it is also useful for your doctor to locate where the cancer has spread.
Patients with papillary thyroid cancer have many treatment options. The selection depends on the stage of the tumor. The options are surgery, radiation therapy, chemotherapy, thyroid hormone treatment, or a combination of these methods. Before treatment starts, ask your health care team about possible side effects and how treatment may change your normal activities. Because cancer treatments often damage healthy cells and tissues, side effects are common. Side effects may not be the same for each person, and they may change from one treatment session to the next.


:*[[Surgery]]: Surgery is the main treatment for papillary thyroid cancer. Usually, surgery of removing the tumor and all or part of the remaining thyroid gland is recommended.
Patients with papillary thyroid cancer have many treatment options. The selection depends on the stage of the [[tumor]]. The options are [[surgery]], [[radioactive iodine]], and [[chemotherapy]]. In case [[surgery]] is not viable, [[radiation therapy]] can also be administered.
:*[[Radiation therapy]]: It includes radioactive Iodine (Radioiodine) therapy and external beam radiation therapy. Radioactive iodine (RAI) known as I-131 can be taken into the body to destroy the thyroid gland and any other thyroid cells including cancer cells. During external beam radiation therapy, the doctors use high-energy rays to destroy cancer cells or slow their rate of growth.
:*[[Chemotherapy]]: Chemotherapy is seldom helpful for most types of papillary thyroid cancer.
:*Thyroid hormone therapy: This treatment is to take daily pills of thyroid hormone. The aim is to help maintain the body's normal metabolism (by replacing missing thyroid hormone) and prevent some thyroid cancers from returning.


===Medications to avoid===
:*[[Surgery]]: [[Surgery]] is the main treatment for papillary thyroid cancer. Usually, surgery of removing the [[tumor]] and all or part of the remaining [[thyroid gland]] is recommended.
{{MedCondContrPI
:*[[Radiation therapy]]: It includes radioactive [[Iodine]] (Radioiodine) therapy and [[external beam radiation therapy]]. [[Radioactive iodine]] ([[Radioactive iodine uptake|RAI]]) known as I-131 can be taken into the body to destroy the [[thyroid gland]] and any other [[thyroid]] cells including cancer cells. During [[external beam radiation therapy]], the doctors use high-energy rays to destroy cancer cells or slow their rate of growth.
 
:*[[Chemotherapy]]: [[Chemotherapy]] is seldom helpful for most types of papillary thyroid cancer.
|MedCond =thyroid cancer|Liraglutide}}
:*Thyroid hormone therapy: This treatment is to take daily pills of [[thyroid hormone]]. The aim is to help maintain the body's normal metabolism (by replacing missing [[thyroid hormone]]) and prevent some [[thyroid cancers]] from returning.


==Where to find medical care for papillary thyroid cancer?==
==Where to find medical care for papillary thyroid cancer?==
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==Prevention of papillary thyroid cancer==
==Prevention of papillary thyroid cancer==
The reasons for the development of papillary thyroid cancer are not clear. Epidemiological data show the following may be helpful:
There are no primary preventive measures available for papillary thyroid cancer, although the following may aid in risk reduction:
 
:*Avoidance of diets low in iodine
:*Avoidance of radiation exposure


:*Consuming an adequate amount of iodine
:*Avoiding [[radiation exposure]]
:*Alert doctors of [[family history]]


==What to expect (Outlook/Prognosis)?==
==What to expect (Outlook/Prognosis)?==
The prognosis of papillary thyroid cancer depends on the following:
The [[prognosis]] of papillary thyroid cancer depends on the following:


:*The stage of the cancer: the size of the tumor, whether the cancer has spread outside the thyroid gland
:*The stage of the cancer: the size of the [[tumor]], whether the [[cancer]] has spread outside the [[thyroid gland]]
:*Whether or not the tumor can be removed by surgery
:*Whether or not the [[tumor]] can be removed by [[surgery]]
:*The patient’s general health
:*Patient's age
:* Size of the [[tumor]]


==Possible complications==
==Possible complications==
*Injury to the voice box and hoarseness after thryoid surgery
*Injury to the [[voice]] box and [[hoarseness]] after [[thyroid]] [[surgery]]
*Low calcium levels from accidental removal of the parathyroid glands during surgery
*Low [[calcium]] levels from accidental removal of the [[parathyroid glands]] during [[surgery]]
*Spread of the cancer to the lungs, bones, or other parts of the body
*Spread of the [[cancer]] to the [[lungs]], [[bones]], or other parts of the body


==Sources==
==Sources==
http://www.nlm.nih.gov/medlineplus/ency/article/001213.htm
https://www.nlm.nih.gov/medlineplus/ency/article/000331.htm
http://www.nlm.nih.gov/medlineplus/thyroidcancer.html


==References==
==References==
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[[Category:Patient information]]
[[Category:Patient information]]
[[Category:Disease]]
[[Category:Endocrine system]]
[[Category:Thyroid disease]]
[[Category:Endocrinology]]
[[Category:Endocrinology]]
[[Category:Mature chapter]]
[[Category:Otolaryngology]]
[[Category:Otolaryngology]]
[[Category:Disease]]
[[Category:Genetic disorders]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Primary care]]
[[Category:Hereditary cancers]]
 
[[Category:Thyroid disease]]
{{WH}}
{{WS}}

Latest revision as of 23:34, 29 July 2020

Papillary thyroid cancer

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

Diagnosis

When to seek urgent medical care?

Treatment options

Where to find medical care for papillary thyroid cancer?

Prevention

What to expect (Outlook/Prognosis)?

Possible complications

Papillary thyroid cancer On the Web

Ongoing Trials at Clinical Trials.gov

Images of Papillary thyroid cancer

Videos on Papillary thyroid cancer

FDA on Papillary thyroid cancer

CDC on Papillary thyroid cancer

Papillary thyroid cancer in the news

Blogs on Papillary thyroid cancer

Directions to Hospitals Treating Papillary thyroid cancer

Risk calculators and risk factors for Papillary thyroid cancer


Template:WikiDoc Sources Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]; Associate Editor(s)-in-Chief: Alison Leibowitz [3]

For the WikiDoc page for this topic, click here

Overview

The thyroid gland, a butterfly-shaped gland in the neck, produces body-regulating hormones. Papillary thyroid cancer starts in the thyroid gland and manifests without early-stage symptoms. As the cancer further develops, noticeable symptoms begin to arise, such as vocal hoarseness, difficulty swallowing, a lump in the neck, which can be felt through the skin, neck or throat pain, and swollen lymph nodes. Treatment options include surgery, radiation therapy, chemotherapy, and thyroid hormone therapy.

What are the symptoms of papillary thyroid cancer?

While patients with early papillary thyroid cancer do not present with any symptoms, as the tumor grows larger people may notice one or more of the following symptoms:

What causes papillary thyroid cancer?

Who is at highest risk?

Clinical data have suggested that the development of papillary thyroid cancer is related to various factors, such as:

  • A diet low in iodine: papillary thyroid cancers are more common in regions characterized by iodine-deficient diets.
  • Radiation exposure
  • Patients over the age of 45-years

Diagnosis

Firstly, a doctor will likely preform a physical exam (noting swollen lymph nodes and lumps in the neck that are perceptible by touch) and review patient medical history. Based upon the physical examination the patient's self-reported symptoms, the doctor may recommend the following tests:

When to seek urgent medical care?

Call your health care provider if symptoms of thyroid cancer develop.

Treatment options

Patients with papillary thyroid cancer have many treatment options. The selection depends on the stage of the tumor. The options are surgery, radioactive iodine, and chemotherapy. In case surgery is not viable, radiation therapy can also be administered.

Where to find medical care for papillary thyroid cancer?

Directions to Hospitals Treating thyroid cancer

Prevention of papillary thyroid cancer

There are no primary preventive measures available for papillary thyroid cancer, although the following may aid in risk reduction:

What to expect (Outlook/Prognosis)?

The prognosis of papillary thyroid cancer depends on the following:

Possible complications

Sources

https://www.nlm.nih.gov/medlineplus/ency/article/000331.htm

References