Palmar plantar erythrodysesthesia history and symptoms: Difference between revisions

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{{Palmar plantar erythrodysesthesia}}
{{Palmar plantar erythrodysesthesia}}
{{CMG}}; '''Associate Editor(s)-in-Chief:''' Zain Fatiwala, M.D.
{{CMG}}; {{AE}}
==Overview==
==Overview==
Palmar plantar erthrodysesthesia usually presents in patients being treated with chemotherapeutic agents. The classic presentation is tingling and/or numbness of the palms and soles that evolve into painful, symmetric, and well0demarcated swelling and red plaques. Subsequently, the skin peels and resolution occurs. Painful red swelling of the hands and feet in a patient receiving chemotherapy is usually enough to make the diagnosis..
The majority of patients with [disease name] are asymptomatic.


==History and symptoms==
OR
The symptoms can occur anywhere between days to months after administration of the offending medication, depending on the dose and speed of administration (Baack and Burgdorf, 1991; Demirçay, 1997;). The patient first experiences tingling and/or numbness of the palms and soles that evolves into painful, symmetric, and well-demarcated swelling and red plaques. This is followed by peeling of the skin and resolution of the symptoms (Apisarnthanarax and Duvic 2003). Painful red swelling of the hands and feet in a patient receiving chemotherapy is usually characteristic presentation. At its maximum, the condition can lead to ulcers and erosions.<ref name="pmid17101468">{{cite journal| author=Janusch M, Fischer M, Marsch WCh, Holzhausen HJ, Kegel T, Helmbold P| title=The hand-foot syndrome--a frequent secondary manifestation in antineoplastic chemotherapy. | journal=Eur J Dermatol | year= 2006 | volume= 16 | issue= 5 | pages= 494-9 | pmid=17101468 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17101468  }}</ref>


It is critical that differential be considered to prevent any adverse outcomes such as Graft versus host disease, Tinea manuum, and hand-foot skin reaction due to tyrosine kinase inhibitor.
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].


==History and Symptoms==
*The majority of patients with [disease name] are asymptomatic.
OR
*The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
*Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 
===History===
Patients with [disease name]] may have a positive history of:
*[History finding 1]
*[History finding 2]
*[History finding 3]
===Common Symptoms===
Common symptoms of [disease] include:
*[Symptom 1]
*[Symptom 2]
*[Symptom 3]
===Less Common Symptoms===
Less common symptoms of [disease name] include
*[Symptom 1]
*[Symptom 2]
*[Symptom 3]
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 15:22, 26 June 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The majority of patients with [disease name] are asymptomatic.

OR

The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History and Symptoms

  • The majority of patients with [disease name] are asymptomatic.

OR

  • The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
  • Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 

History

Patients with [disease name]] may have a positive history of:

  • [History finding 1]
  • [History finding 2]
  • [History finding 3]

Common Symptoms

Common symptoms of [disease] include:

  • [Symptom 1]
  • [Symptom 2]
  • [Symptom 3]

Less Common Symptoms

Less common symptoms of [disease name] include

  • [Symptom 1]
  • [Symptom 2]
  • [Symptom 3]

References