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{{Palmar plantar erythrodysesthesia}}
{{Palmar plantar erythrodysesthesia}}
{{CMG}}
{{CMG}}; {{AE}} {{MC}}


''Synonyms''
{{SK}} PPE; palmar-plantar erythrodysesthesia; palmoplantar erythrodysesthesia, palmoplantar erythema, hand-foot syndrome, peculiar AE, chemotherapy-induced AE, acral erythema (AE), toxic erythema of the palms and soles, palmar-plantar erythema, and Burgdorf’s reaction.
Other names for PPE include acral erythema (AE), palmoplantar erythema, hand-foot syndrome, peculiar AE, and Burgdorf reaction.


==[[Palmar plantar erythrodysesthesia overview|Overview]]==
==[[Palmar plantar erythrodysesthesia overview|Overview]]==


==[[Palmar plantar erythrodysesthesia historical perspective|Historical perspective]]==
==[[Palmar plantar erythrodysesthesia historical perspective|Historical perspective]]==
==[[Palmar plantar erythrodysesthesia classification|Classification]]==


==[[Palmar plantar erythrodysesthesia pathophysiology|Pathophysiology]]==
==[[Palmar plantar erythrodysesthesia pathophysiology|Pathophysiology]]==


==[[Palmar plantar erythrodysesthesia epidemiology and demographics|Epidemiology & Demographics]]==
==[[Palmar plantar erythrodysesthesia epidemiology and demographics|Epidemiology & Demographics]]==
==[[Palmar plantar erythrodysesthesia risk factors|Risk Factors]]==


==[[Palmar plantar erythrodysesthesia causes|Causes]]==
==[[Palmar plantar erythrodysesthesia causes|Causes]]==
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==Diagnosis==
==Diagnosis==
[[Palmar plantar erythrodysesthesia history and symptoms| History and Symptoms]] | [[Palmar plantar erythrodysesthesia physical examination | Physical Examination]] | [[Palmar plantar erythrodysesthesia laboratory findings|Laboratory Findings]] | [[Palmar plantar erythrodysesthesia CT|CT]] | [[Palmar plantar erythrodysesthesia other imaging findings|Other Imaging Findings]] | [[Palmar plantar erythrodysesthesia other diagnostic studies|Other Diagnostic Studies]]
[[Palmar plantar erythrodysesthesia history and symptoms| History and Symptoms]] | [[Palmar plantar erythrodysesthesia physical examination | Physical Examination]] | [[Palmar plantar erythrodysesthesia laboratory findings|Laboratory Findings]] | [[Palmar plantar erythrodysesthesia CT|CT]] | [[Palmar plantar erythrodysesthesia other imaging findings|Other Imaging Findings]] | [[Palmar plantar erythrodysesthesia other diagnostic studies|Other Diagnostic Studies]]
==[[Palmar plantar erythrodysesthesia history and symptoms|History & Symptoms]]==


==Treatment==
==Treatment==
[[Palmar plantar erythrodysesthesia medical therapy|Medical Therapy]] |  [[Palmar plantar erythrodysesthesia surgery|Surgery]] | [[Palmar plantar erythrodysesthesia primary prevention|Primary Prevention]] | [[Palmar plantar erythrodysesthesia secondary prevention|Secondary Prevention]] | [[Palmar plantar erythrodysesthesia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Palmar plantar erythrodysesthesia future or investigational therapies|Future or Investigational Therapies]]
[[Palmar plantar erythrodysesthesia medical therapy|Medical Therapy]] |  [[Palmar plantar erythrodysesthesia surgery|Surgery]] | [[Palmar plantar erythrodysesthesia primary prevention|Primary Prevention]] | [[Palmar plantar erythrodysesthesia secondary prevention|Secondary Prevention]] | [[Palmar plantar erythrodysesthesia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Palmar plantar erythrodysesthesia future or investigational therapies|Future or Investigational Therapies]]
==[[Palmar plantar erythrodysesthesia primary prevention|Primary Prevention]]==


==References==
==References==
* Apisarnthanarax, N and Duvic MM. Dermatologic Complications of Cancer Chemotherapy in Holland-Frei Cancer Medicine - 6th Ed., Ch. 147, Kufe, DW et al editors, BC Decker Inc, Hamilton, Ontario. 2003.
* {{cite journal |author=Baack B, Burgdorf W |title=Chemotherapy-induced acral erythema |journal=J Am Acad Dermatol |volume=24 |issue=3 |pages=457-61 |year=1991 |pmid=2061446}}
* {{cite journal |author=Crider M, Jansen J, Norins A, McHale M |title=Chemotherapy-induced acral erythema in patients receiving bone marrow transplantation |journal=Arch Dermatol |volume=122 |issue=9 |pages=1023-7 |year=1986 |pmid=3527075}}
* {{cite journal |author=Demirçay Z, Gürbüz O, Alpdoğan T, Yücelten D, Alpdoğan O, Kurtkaya O, Bayik M |title=Chemotherapy-induced acral erythema in leukemic patients: a report of 15 cases |journal=Int J Dermatol |volume=36 |issue=8 |pages=593-8 |year=1997 |pmid=9329890}}
* {{cite journal |author=Vukelja S, Baker W, Burris H, Keeling J, Von Hoff D |title=Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with taxotere |journal=J Natl Cancer Inst |volume=85 |issue=17 |pages=1432-3 |year=1993 |pmid=8102408}}
* {{cite journal |author=Zimmerman G, Keeling J, Burris H, Cook G, Irvin R, Kuhn J, McCollough M, Von Hoff D |title=Acute cutaneous reactions to docetaxel, a new chemotherapeutic agent |journal=Arch Dermatol |volume=131 |issue=2 |pages=202-6 |year=1995 |pmid=7857119}}
* {{cite journal |author=Zuehlke R |title=Erythematous eruption of the palms and soles associated with mitotane therapy |journal=Dermatologica |volume=148 |issue=2 |pages=90-2 |year=1974 |pmid=4276191}}
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Oncology]]
[[Category:Oncology]]
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Latest revision as of 17:05, 2 July 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mandana Chitsazan, M.D. [2]

Synonyms and keywords: PPE; palmar-plantar erythrodysesthesia; palmoplantar erythrodysesthesia, palmoplantar erythema, hand-foot syndrome, peculiar AE, chemotherapy-induced AE, acral erythema (AE), toxic erythema of the palms and soles, palmar-plantar erythema, and Burgdorf’s reaction.

Overview

Historical perspective

Classification

Pathophysiology

Epidemiology & Demographics

Risk Factors

Causes

Differentiating Palmar plantar erythrodysesthesia from other Diseases

Natural history, Complications, and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | CT | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

References

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