Osteosarcoma: Difference between revisions

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{{Infobox_Disease
[[File:Osteosarcoma-distal-femur (2).jpg|thumb|Conventional Osteosarcoma of the distal femur of an 18 year old male.Case courtesy of A.Prof Frank Gaillard, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/7621">rID: 7621</a>]]
| Name          = Osteosarcoma
__NOTOC__
| DiseasesDB    = 9392
| ICD10          = {{ICD10|C|40||c|40}}-{{ICD10|C|41||c|40}}
| ICD9          = {{ICD9|170}}
| ICDO          = {{ICDO|9180|3}}
| OMIM          = 259500
| MedlinePlus    = 001650
| MeshID        = D012516
}}
{{Osteosarcoma}}
{{Osteosarcoma}}
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''


{{CMG}}
{{CMG}}; {{AE}}[[User:DrMars|Mohammadmain Rezazadehsaatlou[2]]].
 
'''Associate Editor-In-Chief:''' {{CZ}}
 
{{Editor Help}}


{{SK}} Osteogenic sarcoma; Osteosarcoma; Osteoblastic osteosarcoma; Osteoblastic sarcoma; Osteochondrosarcoma; Telangiectatic osteosarcoma; Small-cell osteosarcoma; Small cell osteosarcoma; Conventional central osteosarcoma; Conventional osteosarcoma; Intraosseous low-grade osteosarcoma; Low grade osteosarcoma; Low-grade osteosarcoma; Intraosseous osteosarcoma; Parosteal osteosarcoma; Periosteal osteosarcoma; Extraskeletal osteosarcoma; High-grade osteosarcoma; High grade osteosarcoma
==[[Osteosarcoma overview|Overview]]==
==[[Osteosarcoma overview|Overview]]==


==[[Osteosarcoma historical perspective|Historical Perspective]]==
==[[Osteosarcoma historical perspective|Historical Perspective]]==
==[[Osteosarcoma classification|Classification]]==


==[[Osteosarcoma pathophysiology|Pathophysiology]]==
==[[Osteosarcoma pathophysiology|Pathophysiology]]==


==[[Osteosarcoma epidemiology and demographics|Epidemiology & Demographics]]==
==[[Osteosarcoma causes|Causes]]==
 
==[[Osteosarcoma differential diagnosis|Differentiating Osteosarcoma from other Diseases]]==
 
==[[Osteosarcoma epidemiology and demographics|Epidemiology and Demographics]]==


==[[Osteosarcoma risk factors|Risk Factors]]==
==[[Osteosarcoma risk factors|Risk Factors]]==
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==[[Osteosarcoma screening|Screening]]==
==[[Osteosarcoma screening|Screening]]==


==[[Osteosarcoma causes|Causes]]==
==[[Osteosarcoma natural history|Natural History, Complications and Prognosis]]==
 
==[[Osteosarcoma differential diagnosis|Differentiating Osteosarcoma]]==
 
==[[Osteosarcoma natural history|Complications & Prognosis]]==


==Diagnosis==
==Diagnosis==
[[Osteosarcoma history and symptoms|History and Symptoms]] | [[Osteosarcoma physical examination|Physical Examination]] | [[Osteosarcoma staging|Staging]] | [[Osteosarcoma laboratory tests|Laboratory tests]] | [[Osteosarcoma electrocardiogram|Electrocardiogram]] | [[Osteosarcoma x ray|X Rays]] | [[Osteosarcoma CT|CT]] | [[Osteosarcoma MRI|MRI]] [[Osteosarcoma echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Osteosarcoma other imaging findings|Other images]] | [[Osteosarcoma other diagnostic studies|Alternative diagnostics]]
[[Osteosarcoma staging|Staging]] | [[Osteosarcoma history and symptoms|History and Symptoms]] | [[Osteosarcoma physical examination|Physical Examination]] | [[Osteosarcoma laboratory findings|Laboratory Findings]] | [[Osteosarcoma biopsy|Biopsy]] | [[Osteosarcoma x ray|X Ray]] | [[Osteosarcoma CT|CT]] | [[Osteosarcoma MRI|MRI]] | [[Osteosarcoma other imaging findings|Other Imaging Findings]] | [[Osteosarcoma other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
[[Osteosarcoma medical therapy|Medical therapy]] | [[Osteosarcoma surgery|Surgical options]] | [[Osteosarcoma primary prevention|Primary prevention]]  | [[Osteosarcoma secondary prevention|Secondary prevention]] | [[Osteosarcoma cost-effectiveness of therapy|Financial costs]] | [[Osteosarcoma future or investigational therapies|Future therapies]]
[[Osteosarcoma medical therapy|Medical Therapy]] | [[Osteosarcoma surgery|Surgery]] | [[Osteosarcoma prevention|Prevention]] | [[Osteosarcoma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Osteosarcoma future or investigational therapies|Future or Investigational Therapies]]


==References==
==Case Studies==
{{Reflist|2}}
:[[Osteosarcoma case study one|Case #1]]
 
==Additional Resources==
*{{cite book |author=James, H. |title=Promises in the Dark |publisher=Bantam Books |location=New York |year=1979 |pages= |isbn=0-553-13453-1 |oclc= |doi=}}  Story of a young girl's osteosarcoma fight and its effect on her relationship with her boyfriend
*{{cite book |author=Trottier, Maxine |title=Terry Fox: A Story of Hope |publisher=Scholastic Canada |location=Markham, Ont |year=2005 |pages= |isbn=0-439-94888-6 |oclc= |doi=}}  About Terry Fox and his quest to raise $25 million for cancer research by running across Canada on his prosthetic leg.  Also ''The Terry Fox Story'', a 1983 movie.
*{{cite book |author=Belshaw, Sheila M. |title=Fly With a Miracle |publisher=Denor Press |location= |year=2001 |pages= |isbn=0 9526056 7 8 |oclc= |doi=}}


==External links==
==External links==
*[http://www.annalssurgicaloncology.org/cgi/content/full/10/5/498 Superior Survivial Seen with Osteosarcoma 2004]
*[http://www.aafp.org/afp/20020315/1123.html Osteosarcoma: A Multidisciplinary Approach to Diagnosis and Treatment]
*[http://www.aafp.org/afp/20020315/1123.html Osteosarcoma: A Multidisciplinary Approach to Diagnosis and Treatment]
*http://www.emedicine.com/PED/topic1684.htm
*http://www.mayoclinic.org/osteosarcoma/index.html
*[http://www.osteosarcomasupport.org Support Group and Information for people with osteosarcoma]
*[http://cancer.gov/cancertopics/pdq/treatment/osteosarcoma/healthprofessional Treatment Information from U.S. National Cancer Institute]  
*[http://cancer.gov/cancertopics/pdq/treatment/osteosarcoma/healthprofessional Treatment Information from U.S. National Cancer Institute]  
* [http://www.liddyshriversarcomainitiative.org/Newsletters/V02N01/Osteosarcoma/osteosarcoma.htm Osteosarcoma by Peter Buecker, MD and Mark Gebhardt, MD]
*[http://www.greendrakkoman.org Green Drakkoman Foundation to assist Warriors of Rare Childhood Cancers]
== Acknowledgements ==
== Acknowledgements ==
The content on this page was first contributed by: [[C. Michael Gibson|C. Michael Gibson M.S., M.D.]]
The content on this page was first contributed by: [[C. Michael Gibson|C. Michael Gibson M.S., M.D.]]


{{Osseous and chondromatous tumors}}
{{Osseous and chondromatous tumors}}
[[de:Osteosarkom]]
[[es:Osteosarcoma]]
[[es:Osteosarcoma]]
[[fr:Ostéosarcome]]
[[fr:Ostéosarcome]]
[[it:Osteosarcoma]]
[[nl:Osteosarcoom]]
[[ja:骨肉腫]]
[[ja:骨肉腫]]
[[pt:Osteossarcoma]]
[[pt:Osteossarcoma]]
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[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Mature chapter]]
[[Category:Mature chapter]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Orthopedics]]

Latest revision as of 15:41, 3 April 2019

Conventional Osteosarcoma of the distal femur of an 18 year old male.Case courtesy of A.Prof Frank Gaillard, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/7621">rID: 7621</a>

Osteosarcoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Osteosarcoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

Biopsy

X Ray

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Osteosarcoma On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Osteosarcoma

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Osteosarcoma

CDC on Osteosarcoma

Osteosarcoma in the news

Blogs on Osteosarcoma

Directions to Hospitals Treating Osteosarcoma

Risk calculators and risk factors for Osteosarcoma

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].

Synonyms and keywords: Osteogenic sarcoma; Osteosarcoma; Osteoblastic osteosarcoma; Osteoblastic sarcoma; Osteochondrosarcoma; Telangiectatic osteosarcoma; Small-cell osteosarcoma; Small cell osteosarcoma; Conventional central osteosarcoma; Conventional osteosarcoma; Intraosseous low-grade osteosarcoma; Low grade osteosarcoma; Low-grade osteosarcoma; Intraosseous osteosarcoma; Parosteal osteosarcoma; Periosteal osteosarcoma; Extraskeletal osteosarcoma; High-grade osteosarcoma; High grade osteosarcoma

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Osteosarcoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging | History and Symptoms | Physical Examination | Laboratory Findings | Biopsy | X Ray | CT | MRI | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

External links

Acknowledgements

The content on this page was first contributed by: C. Michael Gibson M.S., M.D.

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