Nifedipine
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: : Abdurahman Khalil, M.D. [2]
For patient information about Nifedipine, click here.
Synonyms / Brand Names:Adalat®, Adalat 10®, Adalat 20®, Adalat 5®, Adalat CC®, Adalat CR®, Adalat Crono®, Adalat Ft®, Adalat Gits®, Adalat Gits 30®, Adalat LA®, Adalat LP®, Adalat Oros®,Adalat PA®, Adalat Retard®, Adalate®, Adapine®, Adapress®, Alat®, Aldipin®, Alfadal®, Alonix®, Alonix S®, Alpha-Nifedipine Retard®, Angipec®, Anifed®, Anpine®, Apo-Nifed®, Aprical®, Bonacid®, Calcibloc®, Calcigard®, Calcilat®, Camont®, Cardifen®, Cardilat®, Cardionorm®, Chronadalate®, Chronadalate Lp®, Citilat®, Coracten®, Coral®, Cordafen®, Cordaflex®, Cordalat®, Cordicant®, Cordilan®, Cordipin®, Corinfar®, Corotrend®, Corynphar®, Depin®, Dignokonstant®, Dilafed®, Dilcor®, Dipinkor®, Duranifin®, Ecodipi®, Ecodipin®, Ecodipin E®, Fedcor®, Fedcor Retard®, Fenamon®, Fenamon Sr®, Fenihidin®, Fenihidine®, Glopir®, Hadipin®, Hexadilat®, Introcar®, Kordafen®, Macorel, Megalat®, Myogard®, N1fedilat®, Nedipin®, Nicardia®, Nifangin®, Nifar®, Nifdemin®, Nifebene®, Nifecard®, Nifecor®, Nifedepat®, Nifedicor®, Nifedin®, Nifedine®, Nifedipine Retard®, Nifedipres®, Nifedirex LP®, Nifelan®, Nifelat®, Nifelat Q®, Nifelate®, Nifensar XL®, Nificard®, Nifidine®, Nifipen®, Niphedipine®, Orix®, Oxcord®, Pidilat®, Procardia®, Procardia XL®, Sepamit®, Tibricol®, Zenusin®
Overview
Nifedipine is a dihydropyridine calcium channel blocker that primarily blocks L-type calcium channels.[1] Its main uses are as an antianginal (especially in Prinzmetal's angina) and antihypertensive, although a large number of other indications have recently been found for this agent, such as Raynaud's phenomenon, premature labor, and painful spasms of the esophagus such as in cancer and tetanus patients. It is also commonly used for the small subset of pulmonary hypertension patients whose symptoms respond to calcium channel blockers.
Category
FDA Package Insert
NIFEDIPINE®
Indications and Usage | Dosage and Administration | Dosage Forms and Strengths | Contraindications | Warnings | Precautions | Adverse Reactions | Drug Interactions | Use in Specific Populations | Overdosage | Description | Clinical Pharmacology | How Supplied/Storage and Handling | Patient Counseling Information | Labels and Packages
Mechanism of Action
References
- ↑ Hayashi K, Homma K, Wakino S, Tokuyama H, Sugano N, Saruta T, Itoh H (2010). "T-type Ca channel blockade as a determinant of kidney protection". Keio J Med. 59 (3): 84–95. doi:10.2302/kjm.59.84. PMID 20881449.
http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=03be089c-07e5-4f94-bfcc-c6101b311785