Neurofibroma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]

Overview

Neurofibroma may be classified into 5 subtypes: cutaneous/dermal/localized, localized intraneural, subcutaneous, diffuse, intramuscular, plexiform and pigmented neurofibroma. Plexiform neurofibromas may be further sub-classified into diffuse and nodular plexiform.

Classification

Neurofibroma may be classified into following subtypes:[1][2][3][4]

Types of neurofibromas Characteristics/Description
Cutaneous/Dermal/Localized/Sporadic neurofibroma (90%)
Localized Intraneural neurofibroma
Subcutaneous neurofibroma
Diffuse neurofibroma

(superficial)

Intramuscular neurofibroma
Plexiform neurofibroma

(deep)

Pigmented neurofibroma

Plexiform neurofibromas can be further subclassified into following:[5]

Types of neurofibromas Characteristics/Description
Diffuse Plexiform neurofibroma
Nodular Plexiform neurofibroma

References

  1. Wilkinson, Lana M.; Manson, David; Smith, Charles R. (2004). "Best Cases from the AFIP". RadioGraphics. 24 (suppl_1): S237–S242. doi:10.1148/rg.24si035170. ISSN 0271-5333.
  2. http://www.nfmidwest.org/wp-content/uploads/2016/03/Neurofibromas.pdf
  3. https://pubs.rsna.org/doi/10.1148/rg.24si035170#REF8
  4. http://surgpathcriteria.stanford.edu/peripheral-nerve/neurofibroma/
  5. http://www.nfmidwest.org/wp-content/uploads/2016/03/Neurofibromas.pdf


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