Nephrolithiasis resident survival guide

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Definition

Causes

Life Threatening Causes

  • Renal Obstruction
  • Renal Isquaemia
  • Renal Impairment

Common Causes

  • Hypercalciuria
  • Hyperoxaluria
  • Hypernatruria
  • Hypocitraturia
  • Gout
  • Previous chemotherapy for Lymphoma and Leukemia
  • Increced Cystine
  • Drug related stones (Xantines)

Management

Diagnostic Approach

Shown below is an algorithm depicting the diagnostic approach to Nephrolithiasis based on the 2014 Review of the Cleveland Clinic, urological and kidney institute.[1]

 
 
 
 
 
Characterize the symptoms:[2]

Abdominal Pain

❑ Irradiated to the lower abdomen and groin
❑ Acute pain

Urinary urgency
Dysuria
Polyuria
Vomits
Nausea
Malaise

Fever and chills
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Obtain a detailed history:

❑ History of kidney stones

❑ Personal and Family
❑ Treatment
❑ Stone analysis

❑ History of UTI or pyelonephritis
❑ Anatomic Features

❑ Horse shoe kidney
❑ Solitary kidney
❑ Obstruction of uteropelvic junction
❑ Previous Kidney or ureteral surgery

❑ Diseases such as:

Hyperparathyroidism
Renal tubular acidosis
Cystinuria
Gout
Diabetes mellitus type 2 or Insulin resistance
Inflammatory bowel disease
Renal insufficiency
Sarcoidosis
Gastro-intestinal pathology

❑ Drug treatments and regular intake:

❑ Carbonic anhydrase inhibitor
Ephedrine
Sulfadiazine
Calcium and Vitamin D
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Examine the patient:

❑ Measure the blood pressure
❑ Measure the heart rate
❑ Measure the temperature
❑ Abdomen

❑ Tender
❑ Painful
Obesity
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Order labs and tests:

Urinalysis

Microscopic hematuria
❑ Nitrates
Leucocytes
Crystalluria

Hemogram

Complete blood count
❑ Serum electrolytes
Urea
Creatinine

CT
Ultrasound if pregnant
❑ 24 hour urine collection analysis

Calcium
Phosphorus
Magnesium
Uric acid
Oxalate
 
 
 
 

References

  1. Frassetto L, Kohlstadt I (2011). "Treatment and prevention of kidney stones: an update". Am Fam Physician. 84 (11): 1234–42. PMID 22150656.
  2. Miller NL, Lingeman JE (2007). "Management of kidney stones". BMJ. 334 (7591): 468–72. doi:10.1136/bmj.39113.480185.80. PMC 1808123. PMID 17332586.


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