Neoplastic meningitis medical therapy: Difference between revisions

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:*More comfortable for the patient
:*More comfortable for the patient
:*Safer than repated lumbar punctures
:*Safer than repated lumbar punctures
:*Better uniform distribuhnoid of the drug in the subarachnoid space
:*Better uniform distribution of the drug in the subarachnoid space


==References==
==References==

Revision as of 21:33, 22 January 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

The mainstay of therapy for neoplastic meningitis is intrathecal chemotherapy.[1]

Medical Therapy

The various treatment options for neoplastic meningitis include:[1]

 
 
 
 
 
 
 
 
 
 
Treatment of neoplastic meningitis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Intrathecal
chemotherapy
 
 
Radiotherapy
 
 
Surgery
 
 
 
 
 
 
 
 
 
 
 


Chemotherapy

  • The mainstay of therapy for neoplastic meningitis is intrathecal chemotherapy.[1]
  • Chemotherapy can help in treatment of the total involved neuraxis. It may be administered systemically or intrathecally.
  • Chemotherapeutic drugs can be given intrathecally either by lumbar puncture or via an intraventricular reservoir system.
  • Accessing via the intraventricular reservoir system is preferred to lumbar puncture for the following reasons:
  • Simple procedure
  • More comfortable for the patient
  • Safer than repated lumbar punctures
  • Better uniform distribution of the drug in the subarachnoid space

References

  1. 1.0 1.1 1.2 Chamberlain, M. C. (2008). "Neoplastic Meningitis". The Oncologist. 13 (9): 967–977. doi:10.1634/theoncologist.2008-0138. ISSN 1083-7159.


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