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*[[REM sleep]] at the onset of [[sleep]] attack in narcoleptic [[patients]] was first ever recorded and reported by Vogel (1960), an [[observation]] extended by Rechschaffen and Dement in 1967.<ref name="Vogel1960">{{cite journal|last1=Vogel|first1=Gerald|title=Studies in Psychophysiology of Dreams|journal=Archives of General Psychiatry|volume=3|issue=4|year=1960|pages=421|issn=0003-990X|doi=10.1001/archpsyc.1960.01710040091011}}</ref><ref name="pmid6083200">{{cite journal| author=Rechtschaffen A, Dement W| title=Studies on the relation of narcolepsy, cataplexy, and sleep with low voltage random EEG activity. | journal=Res Publ Assoc Res Nerv Ment Dis | year= 1967 | volume= 45 | issue=  | pages= 488-505 | pmid=6083200 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6083200  }} </ref> Hishikawa (1968) studied the [[EEG]] of narcoleptic [[patients]].<ref name="pmid4169745">{{cite journal| author=Hishikawa Y, Nan'no H, Tachibana M, Furuya E, Koida H, Kaneko Z| title=The nature of sleep attack and other symptoms of narcolepsy. | journal=Electroencephalogr Clin Neurophysiol | year= 1968 | volume= 24 | issue= 1 | pages= 1-10 | pmid=4169745 | doi=10.1016/0013-4694(68)90060-6 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4169745  }} </ref> These authors together first articulated the now classical [[hypothesis]] of dissociated [[REM sleep]] and explained some [[symptoms]] of narcolepsy. Their discovery established a multiple [[sleep latency]] [[test]] as a [[standard]] [[diagnostic test]] for narcolepsy in 1970.<ref name="pmid81764">{{cite journal| author=Richardson GS, Carskadon MA, Flagg W, Van den Hoed J, Dement WC, Mitler MM| title=Excessive daytime sleepiness in man: multiple sleep latency measurement in narcoleptic and control subjects. | journal=Electroencephalogr Clin Neurophysiol | year= 1978 | volume= 45 | issue= 5 | pages= 621-7 | pmid=81764 | doi=10.1016/0013-4694(78)90162-1 | pmc=2391074 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=81764  }} </ref><ref name="pmid3809866">{{cite journal| author=Carskadon MA, Dement WC, Mitler MM, Roth T, Westbrook PR, Keenan S| title=Guidelines for the multiple sleep latency test (MSLT): a standard measure of sleepiness. | journal=Sleep | year= 1986 | volume= 9 | issue= 4 | pages= 519-24 | pmid=3809866 | doi=10.1093/sleep/9.4.519 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3809866  }} </ref>
*[[REM sleep]] at the onset of [[sleep]] attack in narcoleptic [[patients]] was first ever recorded and reported by Vogel (1960), an [[observation]] extended by Rechschaffen and Dement in 1967.<ref name="Vogel1960">{{cite journal|last1=Vogel|first1=Gerald|title=Studies in Psychophysiology of Dreams|journal=Archives of General Psychiatry|volume=3|issue=4|year=1960|pages=421|issn=0003-990X|doi=10.1001/archpsyc.1960.01710040091011}}</ref><ref name="pmid6083200">{{cite journal| author=Rechtschaffen A, Dement W| title=Studies on the relation of narcolepsy, cataplexy, and sleep with low voltage random EEG activity. | journal=Res Publ Assoc Res Nerv Ment Dis | year= 1967 | volume= 45 | issue=  | pages= 488-505 | pmid=6083200 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6083200  }} </ref> Hishikawa (1968) studied the [[EEG]] of narcoleptic [[patients]].<ref name="pmid4169745">{{cite journal| author=Hishikawa Y, Nan'no H, Tachibana M, Furuya E, Koida H, Kaneko Z| title=The nature of sleep attack and other symptoms of narcolepsy. | journal=Electroencephalogr Clin Neurophysiol | year= 1968 | volume= 24 | issue= 1 | pages= 1-10 | pmid=4169745 | doi=10.1016/0013-4694(68)90060-6 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4169745  }} </ref> These authors together first articulated the now classical [[hypothesis]] of dissociated [[REM sleep]] and explained some [[symptoms]] of narcolepsy. Their discovery established a multiple [[sleep latency]] [[test]] as a [[standard]] [[diagnostic test]] for narcolepsy in 1970.<ref name="pmid81764">{{cite journal| author=Richardson GS, Carskadon MA, Flagg W, Van den Hoed J, Dement WC, Mitler MM| title=Excessive daytime sleepiness in man: multiple sleep latency measurement in narcoleptic and control subjects. | journal=Electroencephalogr Clin Neurophysiol | year= 1978 | volume= 45 | issue= 5 | pages= 621-7 | pmid=81764 | doi=10.1016/0013-4694(78)90162-1 | pmc=2391074 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=81764  }} </ref><ref name="pmid3809866">{{cite journal| author=Carskadon MA, Dement WC, Mitler MM, Roth T, Westbrook PR, Keenan S| title=Guidelines for the multiple sleep latency test (MSLT): a standard measure of sleepiness. | journal=Sleep | year= 1986 | volume= 9 | issue= 4 | pages= 519-24 | pmid=3809866 | doi=10.1093/sleep/9.4.519 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3809866  }} </ref>
*The first [[Epidemiological study|epidemiological studies]] of narcolepsy were performed by Roth (1980) and Dement (1972-73), revealing a [[prevalence]] of 0.02-0.05% for narcolepsy with [[cataplexy]]. <ref>Roth, Bedrich, and Roger J. Broughton. Narcolepsy and hypersomnia. Basel New York: Karger, 1980. Print.</ref><ref>Dement WC, Zarcone V, Varner V. The prevalence of narcolepsy. Sleep Res., 1: 148-149 1972.</ref><ref>Dement WC, Carskadon M, Ley R. The prevalence of narcolepsy II. Sleep Res., 2: 147, 1973.</ref>
*The first [[Epidemiological study|epidemiological studies]] of narcolepsy were performed by Roth (1980) and Dement (1972-73), revealing a [[prevalence]] of 0.02-0.05% for narcolepsy with [[cataplexy]]. <ref>Roth, Bedrich, and Roger J. Broughton. Narcolepsy and hypersomnia. Basel New York: Karger, 1980. Print.</ref><ref>Dement WC, Zarcone V, Varner V. The prevalence of narcolepsy. Sleep Res., 1: 148-149 1972.</ref><ref>Dement WC, Carskadon M, Ley R. The prevalence of narcolepsy II. Sleep Res., 2: 147, 1973.</ref>
*[[Canine]] narcolepsy in various breeds of dogs was identified and described in 1973, by Knecht and Mitler.
*[[Canine]] narcolepsy in various breeds of dogs was identified and described in 1973, by Knecht and Mitler.<ref name="pmid4736237">{{cite journal| author=Knecht CD, Oliver JE, Redding R, Selcer R, Johnson G| title=Narcolepsy in a dog and a cat. | journal=J Am Vet Med Assoc | year= 1973 | volume= 162 | issue= 12 | pages= 1052-3 | pmid=4736237 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4736237  }} </ref><ref name="pmid4472992">{{cite journal| author=Mitler MM, Boysen BG, Campbell L, Dement WC| title=Narcolepsy-cataplexy in a female dog. | journal=Exp Neurol | year= 1974 | volume= 45 | issue= 2 | pages= 332-40 | pmid=4472992 | doi=10.1016/0014-4886(74)90122-8 | pmc=2391078 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4472992  }} </ref>
*In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
*In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
*In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
*In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].

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References

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  2. Westphal C. Eigenthümliche mit Einschläfen verbundene Anfälle. Arch. Psychiat., 7: 631-635 1877.
  3. Schenck CH, Bassetti CL, Arnulf I, Mignot E (2007). "English translations of the first clinical reports on narcolepsy and cataplexy by Westphal and Gélineau in the late 19th century, with commentary". J Clin Sleep Med. 3 (3): 301–11. PMC 2564780. PMID 17561602.
  4. Janković S, Susić V, Sokić D, Lević Z (1996). "[Dr. John Baptiste Edouard Gélineau]". Srp Arh Celok Lek. 124 (11–12): 331–5. PMID 9132972.
  5. Gélineau J. De la narcolepsie. Gazette des hôpitaux,. 53: 626-628, 1880.
  6. Gélineau JBE. De la narcolepsie. Surgères, Charente-Inférieure: Imprimerie de Surgères, 64, 1881.
  7. Löwenfeld L. Uber Narkolepsie. Munch. Med. Wochenschr., 49: 1041-1045, 1902.
  8. Addie W. IdIopathic narcolepsy: a disease sui generis; with remarks on the mechanism of sleep. Brain, 49: 257-306, 1926.
  9. Wilson SAK. The narcolepsies. Annual Congress Assoc. Phys., June 3: 63-109, 1927.
  10. Daniels LE. Narcolepsy. Medicine, 13(1): 1-122, 1934.
  11. Van Economo C. Sleep as a problem of localization. J. Nerv. Ment. Disease, 71(3): 249-259, 1930.
  12. . doi:10.1159/isbn.978-3-318-05312-8. Missing or empty |title= (help)
  13. YOSS RE, DALY DD (1957). "Criteria for the diagnosis of the narcoleptic syndrome". Proc Staff Meet Mayo Clin. 32 (12): 320–8. PMID 13441766.
  14. Vogel, Gerald (1960). "Studies in Psychophysiology of Dreams". Archives of General Psychiatry. 3 (4): 421. doi:10.1001/archpsyc.1960.01710040091011. ISSN 0003-990X.
  15. Rechtschaffen A, Dement W (1967). "Studies on the relation of narcolepsy, cataplexy, and sleep with low voltage random EEG activity". Res Publ Assoc Res Nerv Ment Dis. 45: 488–505. PMID 6083200.
  16. Hishikawa Y, Nan'no H, Tachibana M, Furuya E, Koida H, Kaneko Z (1968). "The nature of sleep attack and other symptoms of narcolepsy". Electroencephalogr Clin Neurophysiol. 24 (1): 1–10. doi:10.1016/0013-4694(68)90060-6. PMID 4169745.
  17. Richardson GS, Carskadon MA, Flagg W, Van den Hoed J, Dement WC, Mitler MM (1978). "Excessive daytime sleepiness in man: multiple sleep latency measurement in narcoleptic and control subjects". Electroencephalogr Clin Neurophysiol. 45 (5): 621–7. doi:10.1016/0013-4694(78)90162-1. PMC 2391074. PMID 81764.
  18. Carskadon MA, Dement WC, Mitler MM, Roth T, Westbrook PR, Keenan S (1986). "Guidelines for the multiple sleep latency test (MSLT): a standard measure of sleepiness". Sleep. 9 (4): 519–24. doi:10.1093/sleep/9.4.519. PMID 3809866.
  19. Roth, Bedrich, and Roger J. Broughton. Narcolepsy and hypersomnia. Basel New York: Karger, 1980. Print.
  20. Dement WC, Zarcone V, Varner V. The prevalence of narcolepsy. Sleep Res., 1: 148-149 1972.
  21. Dement WC, Carskadon M, Ley R. The prevalence of narcolepsy II. Sleep Res., 2: 147, 1973.
  22. Knecht CD, Oliver JE, Redding R, Selcer R, Johnson G (1973). "Narcolepsy in a dog and a cat". J Am Vet Med Assoc. 162 (12): 1052–3. PMID 4736237.
  23. Mitler MM, Boysen BG, Campbell L, Dement WC (1974). "Narcolepsy-cataplexy in a female dog". Exp Neurol. 45 (2): 332–40. doi:10.1016/0014-4886(74)90122-8. PMC 2391078. PMID 4472992.
  24. Prinzmetal, Myron (1935). "THE USE OF BENZEDRINE FOR THE TREATMENT OF NARCOLEPSY". Journal of the American Medical Association. 105 (25): 2051. doi:10.1001/jama.1935.02760510023006. ISSN 0002-9955.
  25. AKIMOTO H, HONDA Y, TAKAHASHI Y (1960). "Pharmacotherapy in narcolepsy". Dis Nerv Syst. 21: 704–6. PMID 13681922.
  26. Yoss, R. E.; Daly, D. (1959). "Treatment of narcolepsy with Ritalin". Neurology. 9 (3): 171–171. doi:10.1212/WNL.9.3.171. ISSN 0028-3878.

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