Myocarditis differential diagnosis: Difference between revisions

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===Electrocardiogram===
===Electrocardiogram===
While both disorders are associated with [[ST segment elevation]], [[pericarditis]] is also associated with [[PR segment]] depression.
While both disorders are associated with [[ST segment elevation]], [[pericarditis]] is also associated with [[PR segment]] depression.
===Cardiac Biomarkers===
Myocarditis is associated with elevations of the [[CK-MB]] and the [[troponin]], while pericarditis is not.  If [[pericarditis]] is associated with underlying inflammation of the [[myocardium]], then this is called [[myopericarditis]]. In this disorder, there are elevations of the [[cardiac biomarkers]].


==References==
==References==

Revision as of 13:30, 5 September 2011

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Myocarditis presents with chest pain and ST segment elevation. Myocardiits must be distinguished from pericarditis and the life threatening condition of ST elevation myocardial infarction.

Differentiating Myocarditis from ST Segment Elevation Myocardial Infarction

Both diseases present with chest pain, elevated cardiac biomarkers, and focal left ventricular dysfunction. There are two studies that can be used to distinguish the two syndromes:

Coronary Angiography

Coronary angiography can be performed to distinguish myocarditis from ST segment elevation myocardial infarction. ST segment elevation myocardial infarction is associated with either complete or subtotal occlusion of an epicardial coronary artery on coronary angiography.

Cardiac Magnetic Resonance Imaging

Cardiac magnetic resonance imaging is also useful in distinguishing between the two syndromes as well. On cardiac MRI, myocarditis is associated with patchy, non-sentimental, hyperenhancement which is confined to the epicardial layer of the myocardium. In contrast, in ST segment elevation myocardial infarction there is confluent hyperenhancement extending from the endocardium in a distribution that mimics the distribution of the epicardial coronary arteries.

Differentiating Myocarditis from Pericarditis

Both diseases present with chest pain and ST segment elevation. The two conditions can be distinguished by the following studies:

Electrocardiogram

While both disorders are associated with ST segment elevation, pericarditis is also associated with PR segment depression.

Cardiac Biomarkers

Myocarditis is associated with elevations of the CK-MB and the troponin, while pericarditis is not. If pericarditis is associated with underlying inflammation of the myocardium, then this is called myopericarditis. In this disorder, there are elevations of the cardiac biomarkers.

References