Myelofibrosis historical perspective
|
Myelofibrosis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Myelofibrosis historical perspective On the Web |
|
American Roentgen Ray Society Images of Myelofibrosis historical perspective |
|
Risk calculators and risk factors for Myelofibrosis historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2], Sujit Routray, M.D. [3]
Overview
The history of myelofibrosis can be divided into pre- and post-Dameshek era. William Dameshek, a Harvard Medical School graduate and a successful clinical hematologist of his time, grouped together chronic myelogenous leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), primary myelofibrosis (PMF), and erythroleukemia with the reason that a self-perpetuating trilineage myeloproliferation underlined their pathogenesis. He called them 'myeloproliferative disorders'. The first description of primary myelofibrosis (PMF) is credited to a German surgeon, Gustav Heuck. He described the concept in 1879 under the title of ‘Two cases of leukemia with peculiar blood and bone marrow findings’.[1]
Historical Perspective
- Myelofibrosis was first discribed by Gustav Heuck, a German surgeon, in 1879, under the title of 'Two cases of leukemia with peculiar blood and bone marrow findings'.[2]
- The concept of myeloproliferative disorders (MPDs) was described by William Dameshek, in 1951, by bringing together these five clinicopathologic entities: chronic myelogenous leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), primary myelofibrosis (PMF), and erythroleukemia.[2]
- The World Health Organization utilizes the name "chronic idiopathic myelofibrosis", while the International Working Group on Myelofibrosis Research and Treatment calls the disease "primary myelofibrosis".[3]
References
- ↑ Tefferi A (January 2008). "The history of myeloproliferative disorders: before and after Dameshek". Leukemia. 22 (1): 3–13. doi:10.1038/sj.leu.2404946. PMID 17882283.
- ↑ 2.0 2.1 Tefferi, A (2007). "The history of myeloproliferative disorders: before and after Dameshek". Leukemia. 22 (1): 3–13. doi:10.1038/sj.leu.2404946. ISSN 0887-6924.
- ↑ History of myelofibrosis. Wikipedia 2016. https://en.wikipedia.org/wiki/Myelofibrosis. Accessed on March 7, 2016