Myelofibrosis (patient information)

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Myelofibrosis

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

Diagnosis

When to seek urgent medical care?

Treatment options

Where to find medical care for Myelofibrosis?

Prevention

What to expect (Outlook/Prognosis)?

Possible complications

Myelofibrosis On the Web

Ongoing Trials at Clinical Trials.gov

Images of Myelofibrosis

Videos on Myelofibrosis

FDA on Myelofibrosis

CDC on Myelofibrosis

Myelofibrosis in the news

Blogs on Myelofibrosis

Directions to Hospitals Treating Myelofibrosis

Risk calculators and risk factors for Myelofibrosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief:Sabawoon Mirwais, M.B.B.S, M.D.[2] Lakshmi Gopalakrishnan, M.B.B.S. [3]

Synonyms and keywords: Idiopathic myelofibrosis; Myeloid metaplasia; Agnogenic myeloid metaplasia; Primary myelofibrosis; Secondary myelofibrosis

Overview

Myelofibrosis is a disorder of the bone marrow, in which the marrow is replaced by scar (fibrous) tissue.

What are the symptoms of Myelofibrosis?

What causes Myelofibrosis?

  • The disorder usually develops slowly in people over age 50.

Diagnosis

When to seek urgent medical care?

Call for an appointment with your health care provider if symptoms of this disorder develop. Uncontrolled bleeding, shortness of breath, or jaundice that gets worse, need urgent or emergency care.

Treatment options

  • The goal of treatment is to alleviate the symptoms. Treatment may involve:

Where to find medical care for Myelofibrosis?

Directions to Hospitals Treating Myelofibrosis

Prevention of Myelofibrosis

There is no known prevention.

What to expect (Outlook/Prognosis)?

This disorder causes slowly worsening bone marrow failure with severe anemia. Low platelet count leads to easy bleeding. Spleen swelling may slowly get worse.

The average survival of people with primary myelofibrosis is about 5 years. However, some people may survive for decades.

Possible complications

Source

Medlineplus

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