Myelodysplastic syndrome differential diagnosis: Difference between revisions

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{{Myelodysplastic syndrome}}
{{Myelodysplastic syndrome}}
{{CMG}};{{AE}} {{NM}}
{{CMG}};{{AE}} {{NM}} {{ADS}}
==Overview==
==Overview==
Myelodysplastic syndrome must be differentiated from other diseases that cause [[anemia]], [[neutropenia]], and [[thrombocytopenia]], such as: [[aplastic anemia]], [[fanconi anemia]], [[pure red cell aplasia]], [[Shwachman-Diamond syndrome]], [[paroxysmal nocturnal hemoglobinuria]], [[parvovirus B19|parovirus B19 infection]], and [[Vitamin B12|vitamin B12 defeciency]].<ref name=Librepathology3>Differential diagnosis of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 9, 2015</ref><ref name="MerrillSmith2011">{{cite journal|last1=Merrill|first1=Andrea L.|last2=Smith|first2=Hedy|title=Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome|journal=Case Reports in Hematology|volume=2011|year=2011|pages=1–4|issn=2090-6560|doi=10.1155/2011/560106}}</ref><ref name="DeZernSekeres2014">{{cite journal|last1=DeZern|first1=A. E.|last2=Sekeres|first2=M. A.|title=The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure|journal=The Oncologist|volume=19|issue=7|year=2014|pages=735–745|issn=1083-7159|doi=10.1634/theoncologist.2014-0056}}</ref><ref name="WeinzierlArber2012">{{cite journal|last1=Weinzierl|first1=E. P.|last2=Arber|first2=D. A.|title=The Differential Diagnosis and Bone Marrow Evaluation of New-Onset Pancytopenia|journal=American Journal of Clinical Pathology|volume=139|issue=1|year=2012|pages=9–29|issn=0002-9173|doi=10.1309/AJCP50AEEYGREWUZ}}</ref>
Myelodysplastic syndrome must be differentiated from other diseases that cause [[anemia]], [[neutropenia]], and [[thrombocytopenia]], such as: [[aplastic anemia]], [[fanconi anemia]], [[pure red cell aplasia]], [[Shwachman-Diamond syndrome]], [[paroxysmal nocturnal hemoglobinuria]], [[parvovirus B19|parovirus B19 infection]], and [[Vitamin B12|vitamin B12 defeciency]]
==Myelodysplastic syndrome differential diagnosis==
==Myelodysplastic syndrome differential diagnosis==
Myelodysplastic syndrome must be differentiated from other diseases that cause [[anemia]], [[neutropenia]], and [[thrombocytopenia]], such as: [[aplastic anemia]], [[fanconi anemia]], [[pure red cell aplasia]], [[Shwachman-Diamond syndrome]], [[paroxysmal nocturnal hemoglobinuria]], [[parvovirus B19|parovirus B19 infection]], and [[Vitamin B12|vitamin B12 defeciency]].<ref name=Librepathology3>Differential diagnosis of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 9, 2015</ref><ref name="MerrillSmith2011">{{cite journal|last1=Merrill|first1=Andrea L.|last2=Smith|first2=Hedy|title=Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome|journal=Case Reports in Hematology|volume=2011|year=2011|pages=1–4|issn=2090-6560|doi=10.1155/2011/560106}}</ref><ref name="DeZernSekeres2014">{{cite journal|last1=DeZern|first1=A. E.|last2=Sekeres|first2=M. A.|title=The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure|journal=The Oncologist|volume=19|issue=7|year=2014|pages=735–745|issn=1083-7159|doi=10.1634/theoncologist.2014-0056}}</ref><ref name="WeinzierlArber2012">{{cite journal|last1=Weinzierl|first1=E. P.|last2=Arber|first2=D. A.|title=The Differential Diagnosis and Bone Marrow Evaluation of New-Onset Pancytopenia|journal=American Journal of Clinical Pathology|volume=139|issue=1|year=2012|pages=9–29|issn=0002-9173|doi=10.1309/AJCP50AEEYGREWUZ}}</ref>
Myelodysplastic syndrome must be differentiated from other diseases that cause [[anemia]], [[neutropenia]], and [[thrombocytopenia]], such as: [[aplastic anemia]], [[fanconi anemia]], [[pure red cell aplasia]], [[Shwachman-Diamond syndrome]], [[paroxysmal nocturnal hemoglobinuria]], [[parvovirus B19|parovirus B19 infection]], and [[Vitamin B12|vitamin B12 defeciency]].<ref name=Librepathology3>Differential diagnosis of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 9, 2015</ref><ref name="MerrillSmith2011">{{cite journal|last1=Merrill|first1=Andrea L.|last2=Smith|first2=Hedy|title=Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome|journal=Case Reports in Hematology|volume=2011|year=2011|pages=1–4|issn=2090-6560|doi=10.1155/2011/560106}}</ref><ref name="DeZernSekeres2014">{{cite journal|last1=DeZern|first1=A. E.|last2=Sekeres|first2=M. A.|title=The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure|journal=The Oncologist|volume=19|issue=7|year=2014|pages=735–745|issn=1083-7159|doi=10.1634/theoncologist.2014-0056}}</ref><ref name="WeinzierlArber2012">{{cite journal|last1=Weinzierl|first1=E. P.|last2=Arber|first2=D. A.|title=The Differential Diagnosis and Bone Marrow Evaluation of New-Onset Pancytopenia|journal=American Journal of Clinical Pathology|volume=139|issue=1|year=2012|pages=9–29|issn=0002-9173|doi=10.1309/AJCP50AEEYGREWUZ}}</ref>

Revision as of 19:55, 14 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2] Amandeep Singh M.D.[3]

Overview

Myelodysplastic syndrome must be differentiated from other diseases that cause anemia, neutropenia, and thrombocytopenia, such as: aplastic anemia, fanconi anemia, pure red cell aplasia, Shwachman-Diamond syndrome, paroxysmal nocturnal hemoglobinuria, parovirus B19 infection, and vitamin B12 defeciency

Myelodysplastic syndrome differential diagnosis

Myelodysplastic syndrome must be differentiated from other diseases that cause anemia, neutropenia, and thrombocytopenia, such as: aplastic anemia, fanconi anemia, pure red cell aplasia, Shwachman-Diamond syndrome, paroxysmal nocturnal hemoglobinuria, parovirus B19 infection, and vitamin B12 defeciency.[1][2][3][4]

Inherited cytopenia Acquired cytopenia Reactive cytopenia
  • Nutritional deficiency
  • Infections

References

  1. Differential diagnosis of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 9, 2015
  2. Merrill, Andrea L.; Smith, Hedy (2011). "Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome". Case Reports in Hematology. 2011: 1–4. doi:10.1155/2011/560106. ISSN 2090-6560.
  3. DeZern, A. E.; Sekeres, M. A. (2014). "The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure". The Oncologist. 19 (7): 735–745. doi:10.1634/theoncologist.2014-0056. ISSN 1083-7159.
  4. Weinzierl, E. P.; Arber, D. A. (2012). "The Differential Diagnosis and Bone Marrow Evaluation of New-Onset Pancytopenia". American Journal of Clinical Pathology. 139 (1): 9–29. doi:10.1309/AJCP50AEEYGREWUZ. ISSN 0002-9173.


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