Molluscum contagiosum epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
The prevalence of molluscum contagiosum is estimated to be around 8000 cases per 100,000 annually. Molluscum contagiosum is a common disease that tends to affect children and immunocompromised. There is no racial predilection to molluscum contagiosum.
The prevalence of molluscum contagiosum is estimated to be around 8000 cases per 100,000 annually. Molluscum contagiosum is a common disease that tends to affect children and immunocompromised adults. Among children, boys and girls are affected equally by molluscum contagiosum. In adulthood, molluscum contagiosum is more prevalent in men than women . There is no racial predilection to molluscum contagiosum.  


==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Prevalence===
===Prevalence===
*Worldwide, the prevalence of molluscum contagiosum in children aged 0-16 year ranges from a low of 5000 per 100,000 persons  to a high of 11500 per 100,000 persons with an average prevalence of 8000 per 100,000 persons.<ref name="pmid24297468">{{cite journal |vauthors=Olsen JR, Gallacher J, Piguet V, Francis NA |title=Epidemiology of molluscum contagiosum in children: a systematic review |journal=Fam Pract |volume=31 |issue=2 |pages=130–6 |year=2014 |pmid=24297468 |doi=10.1093/fampra/cmt075 |url=}}</ref>
Worldwide, the prevalence of molluscum contagiosum in children aged 0-16 year ranges from 5000 to 11500 per 100,000 persons with an average prevalence of 8000 per 100,000 persons.<ref name="pmid24297468">{{cite journal |vauthors=Olsen JR, Gallacher J, Piguet V, Francis NA |title=Epidemiology of molluscum contagiosum in children: a systematic review |journal=Fam Pract |volume=31 |issue=2 |pages=130–6 |year=2014 |pmid=24297468 |doi=10.1093/fampra/cmt075 |url=}}</ref>
 
===Incidence===
===Incidence===
*Worldwide, the incidence of molluscum contagiosum is 1200-1400 per 100,000 persons.<ref name="pmid24297468">{{cite journal |vauthors=Olsen JR, Gallacher J, Piguet V, Francis NA |title=Epidemiology of molluscum contagiosum in children: a systematic review |journal=Fam Pract |volume=31 |issue=2 |pages=130–6 |year=2014 |pmid=24297468 |doi=10.1093/fampra/cmt075 |url=}}</ref>
Worldwide, the incidence of molluscum contagiosum is 1200-1400 per 100,000 persons per year.<ref name="pmid24297468">{{cite journal |vauthors=Olsen JR, Gallacher J, Piguet V, Francis NA |title=Epidemiology of molluscum contagiosum in children: a systematic review |journal=Fam Pract |volume=31 |issue=2 |pages=130–6 |year=2014 |pmid=24297468 |doi=10.1093/fampra/cmt075 |url=}}</ref>
 
===Case Fatality Rate===
===Case Fatality Rate===
*The case fatality rate of molluscum contagiosum is not available now. Molluscum contagiosum only can lead to fatality in immunocompromised adults, which may be associated with other opportuinistic diseases and thus the fatality rate is hard to determine.<ref name="pmid10210787">{{cite journal |vauthors=Calista D, Boschini A, Landi G |title=Resolution of disseminated molluscum contagiosum with Highly Active Anti-Retroviral Therapy (HAART) in patients with AIDS |journal=Eur J Dermatol |volume=9 |issue=3 |pages=211–3 |year=1999 |pmid=10210787 |doi= |url=}}</ref><ref name="pmid1610701">{{cite journal |vauthors=Koopman RJ, van Merriënboer FC, Vreden SG, Dolmans WM |title=Molluscum contagiosum; a marker for advanced HIV infection |journal=Br. J. Dermatol. |volume=126 |issue=5 |pages=528–9 |year=1992 |pmid=1610701 |doi= |url=}}</ref>
Data on the case fatality rate of molluscum contagiosum is not available. Molluscum contagiosum only can lead to fatality in immunocompromised adults, which may be associated with other [[Opportunistic infection|opportunistic infections]] and thus the fatality rate is difficult to determine.<ref name="pmid10210787">{{cite journal |vauthors=Calista D, Boschini A, Landi G |title=Resolution of disseminated molluscum contagiosum with Highly Active Anti-Retroviral Therapy (HAART) in patients with AIDS |journal=Eur J Dermatol |volume=9 |issue=3 |pages=211–3 |year=1999 |pmid=10210787 |doi= |url=}}</ref><ref name="pmid1610701">{{cite journal |vauthors=Koopman RJ, van Merriënboer FC, Vreden SG, Dolmans WM |title=Molluscum contagiosum; a marker for advanced HIV infection |journal=Br. J. Dermatol. |volume=126 |issue=5 |pages=528–9 |year=1992 |pmid=1610701 |doi= |url=}}</ref>
 
===Age===
===Age===
   
   
*The prevalence of molluscum contagiosum decreases with age.<ref name="pmid28521677">{{cite journal |vauthors=Leung AK, Barankin B, Hon KL |title=Molluscum contagiosum: an update |journal=Recent Pat Inflamm Allergy Drug Discov |volume= |issue= |pages= |year=2017 |pmid=28521677 |doi=10.2174/1872213X11666170518114456 |url=}}</ref><ref name="pmid24297468">{{cite journal |vauthors=Olsen JR, Gallacher J, Piguet V, Francis NA |title=Epidemiology of molluscum contagiosum in children: a systematic review |journal=Fam Pract |volume=31 |issue=2 |pages=130–6 |year=2014 |pmid=24297468 |doi=10.1093/fampra/cmt075 |url=}}</ref><ref name="pmid16384754">{{cite journal |vauthors=Dohil MA, Lin P, Lee J, Lucky AW, Paller AS, Eichenfield LF |title=The epidemiology of molluscum contagiosum in children |journal=J. Am. Acad. Dermatol. |volume=54 |issue=1 |pages=47–54 |year=2006 |pmid=16384754 |doi=10.1016/j.jaad.2005.08.035 |url=}}</ref>
*The prevalence of molluscum contagiosum decreases with age.<ref name="pmid28521677">{{cite journal |vauthors=Leung AK, Barankin B, Hon KL |title=Molluscum contagiosum: an update |journal=Recent Pat Inflamm Allergy Drug Discov |volume= |issue= |pages= |year=2017 |pmid=28521677 |doi=10.2174/1872213X11666170518114456 |url=}}</ref><ref name="pmid24297468">{{cite journal |vauthors=Olsen JR, Gallacher J, Piguet V, Francis NA |title=Epidemiology of molluscum contagiosum in children: a systematic review |journal=Fam Pract |volume=31 |issue=2 |pages=130–6 |year=2014 |pmid=24297468 |doi=10.1093/fampra/cmt075 |url=}}</ref><ref name="pmid16384754">{{cite journal |vauthors=Dohil MA, Lin P, Lee J, Lucky AW, Paller AS, Eichenfield LF |title=The epidemiology of molluscum contagiosum in children |journal=J. Am. Acad. Dermatol. |volume=54 |issue=1 |pages=47–54 |year=2006 |pmid=16384754 |doi=10.1016/j.jaad.2005.08.035 |url=}}</ref>
*Incidence first peaks in preschool/school-aged children, with the greatest incidence being in those aged 1-4 years.<ref name="pmid25161331">{{cite journal |vauthors=Kalasannavar SB, Sawalgimath MP |title=Molluscum contagiosum: A novel Ayurvedic approach |journal=Anc Sci Life |volume=33 |issue=1 |pages=49–51 |year=2013 |pmid=25161331 |pmc=4140023 |doi=10.4103/0257-7941.134606 |url=}}</ref>
*Incidence first peaks in preschool/school-aged children, with the greatest incidence being in those aged 1-4 years.<ref name="pmid25161331">{{cite journal |vauthors=Kalasannavar SB, Sawalgimath MP |title=Molluscum contagiosum: A novel Ayurvedic approach |journal=Anc Sci Life |volume=33 |issue=1 |pages=49–51 |year=2013 |pmid=25161331 |pmc=4140023 |doi=10.4103/0257-7941.134606 |url=}}</ref>
*If diagnosed in adults, molluscum contagiosum will most commonly seen in the 14-20-year age group.<ref name="pmid14996374">{{cite journal |vauthors=Laxmisha C, Thappa DM, Jaisankar TJ |title=Clinical profile of molluscum contagiosum in children versus adults |journal=Dermatol. Online J. |volume=9 |issue=5 |pages=1 |year=2003 |pmid=14996374 |doi= |url=}}</ref>
*If diagnosed in adults, molluscum contagiosum will most commonly be seen in the 18 to 20-year age group.<ref name="pmid14996374">{{cite journal |vauthors=Laxmisha C, Thappa DM, Jaisankar TJ |title=Clinical profile of molluscum contagiosum in children versus adults |journal=Dermatol. Online J. |volume=9 |issue=5 |pages=1 |year=2003 |pmid=14996374 |doi= |url=}}</ref>
===Gender===
===Gender===
*Men and women are affected equally by molluscum contagiosum in children.
*Among children, boys and girls are affected equally by molluscum contagiosum.
*Molluscum contagiosum is more prevalent in men than women in adulthood.
*In adulthood, molluscum contagiosum is more prevalent in men than women .
*Men are more commonly affected with molluscum contagiosum than woman. The male to female ratio is approximately 3 to 1 according to 2 different studies done on adults<ref name="pmid6687557">{{cite journal |vauthors= |title=Sexually transmitted diseases. Extract from the annual report of the Chief Medical Officer of the Department of Health and Social Security of the year 1980 |journal=Br J Vener Dis |volume=59 |issue=2 |pages=134–7 |year=1983 |pmid=6687557 |pmc=1046157 |doi= |url=}}</ref>.  A high proportion of the studied subjects were HIV-positive adults.<ref name="pmid5921341">{{cite journal |vauthors=Overfield TM, Brody JA |title=An epidemiologic study of molluscum contagiosum in Anchorage, Alaska |journal=J. Pediatr. |volume=69 |issue=4 |pages=640–2 |year=1966 |pmid=5921341 |doi= |url=}}</ref><ref name="pmid7928025">{{cite journal |vauthors=Gottlieb SL, Myskowski PL |title=Molluscum contagiosum |journal=Int. J. Dermatol. |volume=33 |issue=7 |pages=453–61 |year=1994 |pmid=7928025 |doi= |url=}}</ref>
*The male to female ratio is approximately 3 to 1 <ref name="pmid6687557">{{cite journal |vauthors= |title=Sexually transmitted diseases. Extract from the annual report of the Chief Medical Officer of the Department of Health and Social Security of the year 1980 |journal=Br J Vener Dis |volume=59 |issue=2 |pages=134–7 |year=1983 |pmid=6687557 |pmc=1046157 |doi= |url=}}</ref>.  A high proportion of the studied subjects were HIV-positive adults.<ref name="pmid5921341">{{cite journal |vauthors=Overfield TM, Brody JA |title=An epidemiologic study of molluscum contagiosum in Anchorage, Alaska |journal=J. Pediatr. |volume=69 |issue=4 |pages=640–2 |year=1966 |pmid=5921341 |doi= |url=}}</ref><ref name="pmid7928025">{{cite journal |vauthors=Gottlieb SL, Myskowski PL |title=Molluscum contagiosum |journal=Int. J. Dermatol. |volume=33 |issue=7 |pages=453–61 |year=1994 |pmid=7928025 |doi= |url=}}</ref>
===Race===
===Race===
*There is no racial predilection to molluscum contagiosum.<ref name="pmid9952381">{{cite journal |vauthors=Konya J, Thompson CH |title=Molluscum contagiosum virus: antibody responses in persons with clinical lesions and seroepidemiology in a representative Australian population |journal=J. Infect. Dis. |volume=179 |issue=3 |pages=701–4 |year=1999 |pmid=9952381 |doi=10.1086/314620 |url=}}</ref>
There is no racial predilection to molluscum contagiosum.<ref name="pmid9952381">{{cite journal |vauthors=Konya J, Thompson CH |title=Molluscum contagiosum virus: antibody responses in persons with clinical lesions and seroepidemiology in a representative Australian population |journal=J. Infect. Dis. |volume=179 |issue=3 |pages=701–4 |year=1999 |pmid=9952381 |doi=10.1086/314620 |url=}}</ref>
===Developed countries and developing countries===
 
*There are no geographic predisposition to molluscum contagiosum.
===Geographic Distribution===
There are no geographic predispositions to molluscum contagiosum.


==References==
==References==

Revision as of 19:33, 28 June 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]

Overview

The prevalence of molluscum contagiosum is estimated to be around 8000 cases per 100,000 annually. Molluscum contagiosum is a common disease that tends to affect children and immunocompromised adults. Among children, boys and girls are affected equally by molluscum contagiosum. In adulthood, molluscum contagiosum is more prevalent in men than women . There is no racial predilection to molluscum contagiosum.

Epidemiology and Demographics

Prevalence

Worldwide, the prevalence of molluscum contagiosum in children aged 0-16 year ranges from 5000 to 11500 per 100,000 persons with an average prevalence of 8000 per 100,000 persons.[1]

Incidence

Worldwide, the incidence of molluscum contagiosum is 1200-1400 per 100,000 persons per year.[1]

Case Fatality Rate

Data on the case fatality rate of molluscum contagiosum is not available. Molluscum contagiosum only can lead to fatality in immunocompromised adults, which may be associated with other opportunistic infections and thus the fatality rate is difficult to determine.[2][3]

Age

  • The prevalence of molluscum contagiosum decreases with age.[4][1][5]
  • Incidence first peaks in preschool/school-aged children, with the greatest incidence being in those aged 1-4 years.[6]
  • If diagnosed in adults, molluscum contagiosum will most commonly be seen in the 18 to 20-year age group.[7]

Gender

  • Among children, boys and girls are affected equally by molluscum contagiosum.
  • In adulthood, molluscum contagiosum is more prevalent in men than women .
  • The male to female ratio is approximately 3 to 1 [8]. A high proportion of the studied subjects were HIV-positive adults.[9][10]

Race

There is no racial predilection to molluscum contagiosum.[11]

Geographic Distribution

There are no geographic predispositions to molluscum contagiosum.

References

  1. 1.0 1.1 1.2 Olsen JR, Gallacher J, Piguet V, Francis NA (2014). "Epidemiology of molluscum contagiosum in children: a systematic review". Fam Pract. 31 (2): 130–6. doi:10.1093/fampra/cmt075. PMID 24297468.
  2. Calista D, Boschini A, Landi G (1999). "Resolution of disseminated molluscum contagiosum with Highly Active Anti-Retroviral Therapy (HAART) in patients with AIDS". Eur J Dermatol. 9 (3): 211–3. PMID 10210787.
  3. Koopman RJ, van Merriënboer FC, Vreden SG, Dolmans WM (1992). "Molluscum contagiosum; a marker for advanced HIV infection". Br. J. Dermatol. 126 (5): 528–9. PMID 1610701.
  4. Leung AK, Barankin B, Hon KL (2017). "Molluscum contagiosum: an update". Recent Pat Inflamm Allergy Drug Discov. doi:10.2174/1872213X11666170518114456. PMID 28521677.
  5. Dohil MA, Lin P, Lee J, Lucky AW, Paller AS, Eichenfield LF (2006). "The epidemiology of molluscum contagiosum in children". J. Am. Acad. Dermatol. 54 (1): 47–54. doi:10.1016/j.jaad.2005.08.035. PMID 16384754.
  6. Kalasannavar SB, Sawalgimath MP (2013). "Molluscum contagiosum: A novel Ayurvedic approach". Anc Sci Life. 33 (1): 49–51. doi:10.4103/0257-7941.134606. PMC 4140023. PMID 25161331.
  7. Laxmisha C, Thappa DM, Jaisankar TJ (2003). "Clinical profile of molluscum contagiosum in children versus adults". Dermatol. Online J. 9 (5): 1. PMID 14996374.
  8. "Sexually transmitted diseases. Extract from the annual report of the Chief Medical Officer of the Department of Health and Social Security of the year 1980". Br J Vener Dis. 59 (2): 134–7. 1983. PMC 1046157. PMID 6687557.
  9. Overfield TM, Brody JA (1966). "An epidemiologic study of molluscum contagiosum in Anchorage, Alaska". J. Pediatr. 69 (4): 640–2. PMID 5921341.
  10. Gottlieb SL, Myskowski PL (1994). "Molluscum contagiosum". Int. J. Dermatol. 33 (7): 453–61. PMID 7928025.
  11. Konya J, Thompson CH (1999). "Molluscum contagiosum virus: antibody responses in persons with clinical lesions and seroepidemiology in a representative Australian population". J. Infect. Dis. 179 (3): 701–4. doi:10.1086/314620. PMID 9952381.

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