Mitral valve prolapse causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Farman Khan, MD, MRCP [2]

Overview

Mitral valve prolapse (MVP) is a valvular heart disease characterized by the displacement of an abnormally thickened mitral valve leaflet into the left atrium during systole. Common causes of MVP include Marfan's syndrome, myxomatous degeneration of the mitral valve, papillary muscle infarction and papillary muscle trauma.

Causes

Common Causes

Causes by Organ System

Cardiovascular ST elevation myocardial infarction, severe mitral annular calcification , ruptured chordae , rheumatic heart disease, papillary muscle dysfunction, myxomatous mitral valve prolapse , hypertrophic cardiomyopathy, forme fruste Barlow disease, Ebstein's anomaly , chordal rupture, cardiomegaly, bacterial endocarditis, congenital heart disease, acute myocardial ischemia
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine Graves disease
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic Turner Syndrome, spastic ataxia, Charlevoix-Saguenay type, osteogenesis imperfecta, X-linked familial mitral valve prolapse, autosomal dominant familial mitral valve prolapse ,MASS phenotype, Marfan-like syndrome Boileau type, Marfan syndrome , Hunter-Mcdonald syndrome, Furlong-Kurczynski-Hennessy syndrome
Hematologic Von Willebrand disease, sickle cell disease
Iatrogenic No underlying causes
Infectious Disease Infective endocarditis, acute rheumatic fever
Musculoskeletal/Orthopedic Scoliosis, pectus excavatum, dermato-cardio-skeletal syndrome Borrone type
Neurologic No underlying causes
Nutritional/Metabolic Scurvy
Obstetric/Gynecologic Pregnancy
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte Polycystic kidney disease
Rheumatology/Immunology/Allergy SLE, pseudoxanthoma elasticum, polyarteritis nodosa, mixed connective tissue disease, Ehlers-Danlos syndrome type I, Ehlers-Danlos syndrome type II, Ehlers-Danlos syndrome Type V, connective tissue disease
Sexual No underlying causes
Trauma Trauma to mitral valve
Urologic No underlying causes
Miscellaneous Stickler Syndrome, Leopard syndrome, idiopathic, fibroelastic deficiency, Dahlberg syndrome, Beals syndrome

Causes in Alphabetical Order

References

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