Microscopic polyangiitis history and symptoms: Difference between revisions

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==Overview==
==Overview==
Obtaining a complete history is an important aspect in making a clinical diagnosis of Microscopic polyangiitis. As it can help differentiate between the ANCA associated vasculitis and other possible causes that may mimic the disease. There are many similarities that are present between ANCA associated vasculitis and Microscopic polyangiitis. A history and clinical symptoms can help assess the disease.   
Obtaining a complete history is an critical aspect in making a clinical diagnosis of Microscopic polyangiitis.As it can help differentiate between the Antineutrophil cytoplasmic antibodies(ANCA) associated vasculitis and other possible causes that may mimic the disease. There are many similarities that are present between ANCA associated vasculitis and Microscopic polyangiitis. A history and clinical symptoms can help assess the disease.   


== History and Symptoms ==
== History and Symptoms ==
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Obtaining a complete history is an important aspect in making a clinical diagnosis of Microscopic polyangiitis. As it can help differentiate between the ANCA associated vasculitis and other possible causes that may mimic the disease.  
Obtaining a complete history is an important aspect in making a clinical diagnosis of Microscopic polyangiitis. As it can help differentiate between the ANCA associated vasculitis and other possible causes that may mimic the disease.  


===Signs and Symptoms===
===Common Symptoms===
The initial signs that are present in patients with Microscopic polyangiitis are non-specific in nature. The following are signs and symptoms of Microscopic polyangiitis:  
Common symptoms of Microscopic polyangiitis include:  
* Renal inflammation (glomerulonephritis)
* Weight loss 


'''Most commonly seen signs'''
* Skin lesions
* renal inflammation (glomerulonephritis)
* weight loss 


* skin lesions
* Nerve damage
* Pyrexia


* nerve damage
* Weight loss
* pyrexia
* Malaise
'''Constitutional Symptoms'''
* Fatigue
* weight loss
* Pyrexia
* malaise
 
* fatigue
* Conjunctivitis
* pyrexia
* Episcleritis
'''Ocular involvement:'''
* Uveitis
* conjunctivitis
 
* episcleritis
* Palpable purpura
* uveitis
* Vesiculobullous lesions
'''Skin involvement:'''
 
* palpable purpura
=== Less Common Symptoms ===
* vesiculobullous lesions
Less Common Symptoms of Microscopic polyangiitis include:
* splinter hemorrhages
* Splinter hemorrhages
'''Peripheral Nervous System:'''
 
* mononeuritis multiplex
* Mononeuritis multiplex
* numbness/ tingling  
* Numbness/ tingling  
* muscle wasting
* Muscle wasting
'''Joint involvement:'''
 
* myalgia
* Myalgia
* arthralgia
* arthralgia
* arthritis
* Arthritis
'''Renal involvement:'''
* hematuria
* protienuria
* red cell casts
'''Pulmonary involvement:'''
* alveolar hemorrhage
* pulmonary infiltrates


* Hematuria
* Proteinuria
* Red cell cast
==References==
==References==
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Revision as of 19:51, 19 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]

Overview

Obtaining a complete history is an critical aspect in making a clinical diagnosis of Microscopic polyangiitis.As it can help differentiate between the Antineutrophil cytoplasmic antibodies(ANCA) associated vasculitis and other possible causes that may mimic the disease. There are many similarities that are present between ANCA associated vasculitis and Microscopic polyangiitis. A history and clinical symptoms can help assess the disease.

History and Symptoms

History

Obtaining a complete history is an important aspect in making a clinical diagnosis of Microscopic polyangiitis. As it can help differentiate between the ANCA associated vasculitis and other possible causes that may mimic the disease.

Common Symptoms

Common symptoms of Microscopic polyangiitis include:

  • Renal inflammation (glomerulonephritis)
  • Weight loss
  • Skin lesions
  • Nerve damage
  • Pyrexia
  • Weight loss
  • Malaise
  • Fatigue
  • Pyrexia
  • Conjunctivitis
  • Episcleritis
  • Uveitis
  • Palpable purpura
  • Vesiculobullous lesions

Less Common Symptoms

Less Common Symptoms of Microscopic polyangiitis include:

  • Splinter hemorrhages
  • Mononeuritis multiplex
  • Numbness/ tingling
  • Muscle wasting
  • Myalgia
  • arthralgia
  • Arthritis
  • Hematuria
  • Proteinuria
  • Red cell cast

References

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