Microangiopathic hemolytic anemia medical therapy: Difference between revisions
Jump to navigation
Jump to search
MydahSajid (talk | contribs) No edit summary |
MydahSajid (talk | contribs) No edit summary |
||
| Line 3: | Line 3: | ||
* [[Microangiopathic hemolytic anemia]] is a medical emergency and requires prompt treatment. | * [[Microangiopathic hemolytic anemia]] is a medical emergency and requires prompt treatment. | ||
* Therapeutic [[plasmapheresis]] is the treatment of choice. It should be instituted immediately in patients with high clinical suspicion of [[microangiopathic hemolytic anemic]] before the results of confirmatory diagnostic tests like ADAM TS13 assay<ref name="pmid27754896">{{cite journal| author=Arnold DM, Patriquin CJ, Nazy I| title=Thrombotic microangiopathies: a general approach to diagnosis and management. | journal=CMAJ | year= 2017 | volume= 189 | issue= 4 | pages= E153-E159 | pmid=27754896 | doi=10.1503/cmaj.160142 | pmc=5266569 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27754896 }} </ref>. | |||
* If [[plasmapheresis]] is unavailable, [[patient]]s can be administered large volume [[plasma]] or [[FFP]]s. This treatment is not as efficacious as [[plasmapheresis]], but it can be suitable alternative<ref name="pmid2062330">{{cite journal| author=Rock GA, Shumak KH, Buskard NA, Blanchette VS, Kelton JG, Nair RC | display-authors=etal| title=Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group. | journal=N Engl J Med | year= 1991 | volume= 325 | issue= 6 | pages= 393-7 | pmid=2062330 | doi=10.1056/NEJM199108083250604 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2062330 }} </ref> . | |||
* Patients should be given [[folic acid|folic acid (oral]] as [[patient]]s can develop [[folate]] deficiency due to ongoing [[hemolysis]] <ref name="pmid22624596">{{cite journal| author=Scully M, Hunt BJ, Benjamin S, Liesner R, Rose P, Peyvandi F | display-authors=etal| title=Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies. | journal=Br J Haematol | year= 2012 | volume= 158 | issue= 3 | pages= 323-35 | pmid=22624596 | doi=10.1111/j.1365-2141.2012.09167.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22624596 }} </ref>. | |||
Please help WikiDoc by adding content here. It's easy! Click [[Help:How_to_Edit_a_Page|here]] to learn about editing. | Please help WikiDoc by adding content here. It's easy! Click [[Help:How_to_Edit_a_Page|here]] to learn about editing. | ||
Revision as of 10:51, 30 January 2021
|
Microangiopathic hemolytic anemia Microchapters |
|
Differentiating Microangiopathic hemolytic anemia from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Microangiopathic hemolytic anemia medical therapy On the Web |
|
American Roentgen Ray Society Images of Microangiopathic hemolytic anemia medical therapy |
|
Microangiopathic hemolytic anemia medical therapy in the news |
|
Directions to Hospitals Treating Microangiopathic hemolytic anemia |
|
Risk calculators and risk factors for Microangiopathic hemolytic anemia medical therapy |
Associate Editor(s)-in-Chief: Mydah Sajid, MD[1]
- Microangiopathic hemolytic anemia is a medical emergency and requires prompt treatment.
- Therapeutic plasmapheresis is the treatment of choice. It should be instituted immediately in patients with high clinical suspicion of microangiopathic hemolytic anemic before the results of confirmatory diagnostic tests like ADAM TS13 assay[1].
- If plasmapheresis is unavailable, patients can be administered large volume plasma or FFPs. This treatment is not as efficacious as plasmapheresis, but it can be suitable alternative[2] .
- Patients should be given folic acid (oral as patients can develop folate deficiency due to ongoing hemolysis [3].
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.
References
- ↑ Arnold DM, Patriquin CJ, Nazy I (2017). "Thrombotic microangiopathies: a general approach to diagnosis and management". CMAJ. 189 (4): E153–E159. doi:10.1503/cmaj.160142. PMC 5266569. PMID 27754896.
- ↑ Rock GA, Shumak KH, Buskard NA, Blanchette VS, Kelton JG, Nair RC; et al. (1991). "Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group". N Engl J Med. 325 (6): 393–7. doi:10.1056/NEJM199108083250604. PMID 2062330.
- ↑ Scully M, Hunt BJ, Benjamin S, Liesner R, Rose P, Peyvandi F; et al. (2012). "Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies". Br J Haematol. 158 (3): 323–35. doi:10.1111/j.1365-2141.2012.09167.x. PMID 22624596.