Microangiopathic hemolytic anemia causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mydah Sajid, MD[2]
Overview
Microangiopathic hemolytic anemia is a clinical manifestation of a large number of diseases. The gentic mutations make some patients prone to microangiopathic hemolytic anemia.
Causes
The most important causes are[1]:
- Aortic Stenosis (most common cause of MAHA)
- Thrombotic thrombocytopenic purpura (TTP)
- Hemolytic uremic syndrome (HUS)
- Disseminated intravascular coagulation (DIC)
- Drug Side Effect- Cyclosporine
- HELLP syndrome and eclampsia
- Heparin-induced thrombocytopenia (HIT)
- Severe glomerulonephritis
- Several other rare causes
References
- ↑ Kottke-Marchant K (2017). "Diagnostic approach to microangiopathic hemolytic disorders". Int J Lab Hematol. 39 Suppl 1: 69–75. doi:10.1111/ijlh.12671. PMID 28447417.