Malaria history and symptoms: Difference between revisions

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* [[Joint pain]]
* [[Joint pain]]
* [[Muscle pain]]
* [[Muscle pain]]
* [[Abnormal posturing]] (children)




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* [[Diarrhea]]
* [[Diarrhea]]
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* [[Abdominal cramps]]
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* Bloody urine
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* [[Convulsions]]
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* Feeling of tingling in the skin
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The bloodstream parasites of P. falciparum infections are often asynchronous and may produce continuous fever. In other infections, fever may be cyclical, recurring every 48 or 72 hours, depending on the species and synchrony of the replicating parasites. Parasite subpopulations on different cycles in the blood- stream may produce complicated fever patterns. Patients with cyclical fevers may be relatively asymptomatic during afebrile periods.
In other infections, fever may be cyclical, recurring every 48 or 72 hours, depending on the species and synchrony of the replicating parasites. Parasite subpopulations on different cycles in the blood- stream may produce complicated fever patterns. Patients with cyclical fevers may be relatively asymptomatic during afebrile periods.


Particular elements from the history and physical examination, when considered together, may be suggestive of the diagnosis of malaria.372-374 Cyclical paroxysms of chills and rigors, fever, and drenching sweats are characteristic although not necessarily specific for malaria. A travel history that reveals risk of exposure months to years before in an endemic region is an alert for malaria and should always be sought in presentations of fever. Findings on physical exami- nation may include pallor and hepatosplenomegaly. Rarely, acute Plas- modium infections present with splenic rupture requiring surgery or conservative management.375,376 Findings such as jaundice, diminished consciousness, or convulsions indicate severe malaria (see later). Rash, lymphadenopathy, and signs of pulmonary consolidation are distinctly uncommon.  
Cyclical paroxysms of chills and rigors, fever, and drenching sweats are characteristic although not necessarily specific for malaria.  
 
A travel history that reveals risk of exposure months to years before in an endemic region is an alert for malaria and should always be sought in presentations of fever.  
 
Findings on physical examination may include pallor and hepatosplenomegaly. Rarely, acute Plasmodium infections present with splenic rupture requiring surgery or conservative management.
 
Findings such as jaundice, diminished consciousness, or convulsions indicate severe malaria (see later). Rash, lymphadenopathy, and signs of pulmonary consolidation are distinctly uncommon.  




* The classical symptom of malaria is cyclical occurrence of sudden coldness followed by rigor and then fever and sweating lasting four to six hours, occurring every two days in ''P. vivax'' and ''P. ovale'' infections, while every three for ''P. malariae''.<ref name=RBMarmenia>[http://www.malaria.am/eng/pathogenesis.php Malaria life cycle & pathogenesis]. Malaria in Armenia. Accessed October 31, 2006.</ref>
* The classical symptom of malaria is cyclical occurrence of sudden coldness followed by rigor and then fever and sweating lasting four to six hours, occurring every two days in ''P. vivax'' and ''P. ovale'' infections, while every three for ''P. malariae''.<ref name=RBMarmenia>[http://www.malaria.am/eng/pathogenesis.php Malaria life cycle & pathogenesis]. Malaria in Armenia. Accessed October 31, 2006.</ref>
* ''P. falciparum'' can have recurrent fever every 36-48 hours or a less pronounced and almost continuous fever.  
* ''P. falciparum'' can have recurrent fever every 36-48 hours or a less pronounced and almost continuous fever.  
* For reasons that are poorly understood, but which may be related to high [[intracranial pressure]], children with malaria frequently exhibit [[abnormal posturing]], a sign indicating severe brain damage.<ref name="Idro ">{{cite journal | last =Idro  | first =R | authorlink = | coauthors =Otieno G, White S, Kahindi A, Fegan G, Ogutu B, Mithwani S, Maitland K, Neville BG, Newton CR | title = Decorticate, decerebrate and opisthotonic posturing and seizures in Kenyan children with cerebral malaria| journal =Malaria Journal | volume =4 | issue =57 | pages = | publisher = | date = | url =http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=16336645 | doi = | id =PMID 16336645 | accessdate =2007-01-21 }} </ref>
*  Malaria has been found to cause cognitive impairments, especially in children. It causes widespread [[anemia]] during a period of rapid brain development and also direct brain damage. This neurologic damage results from cerebral malaria to which children are more vulnerable.<ref>Boivin, M.J., "[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12394524&dopt=Citation Effects of early cerebral malaria on cognitive ability in Senegalese children]," ''Journal of Developmental and Behavioral Pediatrics'' 23, no. 5 (October 2002): 353&ndash;64. Holding, P.A. and Snow, R.W., "[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11425179&dopt=Citation Impact of Plasmodium falciparum malaria on performance and learning: review of the evidence]," ''American Journal of Tropical Medicine and Hygiene'' 64, suppl. nos. 1&ndash;2 (January&ndash;February 2001): 68&ndash;75.</ref>


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Revision as of 15:46, 24 July 2014

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Overview

Malaria parasites are transmitted by female Anopheles mosquitoes. The parasites multiply within red blood cells, causing symptoms that include symptoms of anemia (light headedness, shortness of breath, tachycardia etc.), as well as other general symptoms such as fever, chills, nausea, flu-like illness, and in severe cases, coma and death.


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