Malabsorption causes

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Malabsorption

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Overview

Classification

Infection
Structural defect
Digestive failure
Systemic disease
Iatrogenic

Differentiating Malabsorption from other Diseases

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maheep Sangha, M.B.B.S. Luke Rusowicz-Orazem, B.S.

Overview

Malabsorption syndrome is commonly caused by gastroenterological conditions, including bacterial infections and other sources of liver, intestine, and pancreatic inflammation. It is also commonly caused by sources of anemia.

Causes[1]

Life Threatening Causes

Common Causes

Causes by Organ System

Cardiovascular Abetalipoproteinemia, Anderson disease, Apolipoprotein b deficiency, Cholesterol ester storage disease, Strictures, Systemic sclerosis 
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic Cholestatic jaundice, Collagen vascular diseases
Drug Side Effect Colchicine, Colestyramine, Efavirenz, Laxative abuse, Metformin, Neomycin, Prolonged antibiotic use
Ear Nose Throat No underlying causes
Endocrine Addison's disease, Autoimmune polyendocrine syndrome type 1, Hyperparathyroidism , Hyperthyroidism, Hypoparathyroidism, Hypothyroidism 
Environmental No underlying causes
Gastroenterologic Alagille syndrome, Atrophic gastritis , B12 malabsorption, Bile acid malabsorption syndrome, Bile salt malabsorption, Biliary atresia, Blind loops, Canada-cronkhite syndrome, Carcinoma of pancreas, Celiac disease, Celiac sprue, Cholestasis, Cholestatic jaundice, Chronic cholestasis, Chronic granulomatous disease, Chronic pancreatitis, Chylomicron retention disease, Cirrhosis, Cow's milk intolerance, Crohn's disease, Disaccharidase deficiency, Diverticulae, Eosinophilic gastroenteropathy, Fistulae, Gallbladder disease, Giardia lamblia, Giardiasis, Graft versus host disease, Hiv related malabsorption, Ileal disease , Intestinal disaccharidase deficiency, Intestinal enteropeptidase deficiency, Intestinal lymphangiectasia, Intestinal lymphoma, Intestinal radiation therapy, Intestinal surgery, Intestinal trauma, Intestinal tuberculosis, Lactase deficiency , Laxative abuse, Liver disease, Menetrier disease, Obstructive jaundice, Pancreatic insufficiencies, Pancreatitis, Pearson marrow-pancreas syndrome, Post billroth ii procedure, Postgastrectomy syndrome, Radiation enteritis, Short bowel syndrome, Short gut syndrome, Shwachman-diamond syndrome, Soya milk intolerance, Terminal ileal disease, Trichohepatoenteric syndrome 1, Tropical sprue, Ulcerative colitis, Whipple's disease, Zollinger-ellison syndrome
Genetic Alagille syndrome, Canada-cronkhite syndrome, Disaccharidase deficiency, Hartnup's disease, Johanson-blizzard syndrome, Trypsinogen deficiency
Hematologic 3-beta-hydroxy-delta-5-c27-steroid oxidoreductase deficiency, Abetalipoproteinemia, Apolipoprotein b deficiency, B12 malabsorption, Common variable hypogammaglobulinaemia, Diabetes mellitus, Eosinophilic gastroenteropathy, Hypogammaglobulinaemia, Ileal disease , Obstructive jaundice, Pernicious anemia , Shwachman-diamond syndrome, Small bowel lymphoma, Sucrase-isomaltase deficiency, Sucrose intolerance, Terminal ileal disease
Iatrogenic Intestinal radiation therapy, Intestinal surgery, Post billroth ii procedure, Postgastrectomy syndrome, Radiation enteritis
Infectious Disease Aids, Bacterial overgrowth, Blind loops, Fasciolopsis buski, Fish tape worm, Giardia lamblia, Giardiasis, Hiv related malabsorption, Hookworm, Intestinal tuberculosis, Pancreatitis, Strongyloidiasis, Whipple's disease
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic Diabetes mellitus, Malnutrition
Obstetric/Gynecologic No underlying causes
Oncologic Carcinoid syndrome, Carcinoma of pancreas, Intestinal lymphoma, Lymphoma , Mastocytosis, Small bowel lymphoma, Zollinger-ellison syndrome
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte Gallbladder disease
Rheumatology/Immunology/Allergy Alpha heavy chain disease, Amyloidosis, Celiac disease, Celiac sprue, Cow's milk intolerance, Crohn's disease, Cystic fibrosis, Mastocytosis, Soya milk intolerance
Sexual Aids
Trauma Intestinal trauma
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

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References

  1. M. S Losowsky,. Malabsorption in clinical practice. Edinburgh: Churchill Livingstone. ISBN 0-443-01007-2.

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