Macrocytic anemia risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]
Overview
Common risk factors of megaloblastic anemia include nutritional factors like alcoholism, elderly, pregnant, veganms; malabsorptive syndromes.
Risk Factors
Common risk factors of megaloblastic anemia:
- Folate deficiency
- Nutritionally deficient - Elderly, alcohol, narcotic abuse
- Those with increased demand: pregnancy, infancy, low grade hemolysis, malignancy or chronic hemodialysis.
- Autoimmune disease such as Hashimoto’s, vitiligo, diabetes, adrenal insufficiency, etc. (Schmitt’s Syndrome).
- Strict Vegans and/or their infant
- Malabsorptive disorders such as blind loops/bacterial overgrowth, Sprue, Whipple’s and Crohn’s can malabsorb folate and B12.
- D.Latum is a competitor for B12 absorption. This entity is most commonly found in Scandinavia.