Macrocytic anemia risk factors: Difference between revisions

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Revision as of 20:45, 29 August 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]

Common risk factors of megaloblastic anemia include nutritional factors like alcoholism, elderly, pregnant, veganms; malabsorptive syndromes.

Common risk factors of megaloblastic anemia:

Folate deficiency
- Nutritionally deficient - Elderly, alcohol, narcotic abuse
- Those with increased demand: pregnancy, infancy, low grade hemolysis, malignancy or chronic hemodialysis.
Autoimmune disease such as Hashimoto’s, vitiligo, diabetes, adrenal insufficiency, etc. (Schmitt’s Syndrome).
Strict Vegans and/or their infant
Malabsorptive disorders such as blind loops/bacterial overgrowth, Sprue, Whipple’s and Crohn’s can malabsorb folate and B12.
D.Latum is a competitor for B12 absorption. This entity is most commonly found in Scandinavia.

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Macrocytic anemia}}
-{{CMG}}
+{{CMG}} {{AE}}{{ADS}}
 ==Overview==
-==Risk Factors==
+Common risk factors of megaloblastic anemia include nutritional factors like alcoholism, elderly, pregnant, veganms; malabsorptive syndromes.
+==Risk Factors==
+Common risk factors of megaloblastic anemia:
 * Folate deficiency
 ** Nutritionally deficient - Elderly, alcohol, narcotic abuse
 ** Those with increased demand: [[pregnancy]], [[infancy]], low grade [[hemolysis]], [[malignancy]] or chronic [[hemodialysis]].
-* Pernicious Anemia (PA) is the most common cause of B12 deficiency in the US and is associated with other autoimmune disease such as Hashimoto’s, vitiligo, diabetes, adrenal insufficiency, etc. (Schmitt’s Syndrome).
+* Autoimmune disease such as Hashimoto’s, vitiligo, diabetes, adrenal insufficiency, etc. (Schmitt’s Syndrome).
-* Strict Vegans and/or their infants can become B12 deficient from poor intake.
+* Strict Vegans and/or their infant
-* Patients with malabsorptive disorders such as blind loops/bacterial overgrowth, Sprue, Whipple’s and Crohn’s can malabsorb folate and B12.  D.Latum is a competitor for B12 absorption. This entity is most commonly found in Scandinavia.
+* Malabsorptive disorders such as blind loops/bacterial overgrowth, Sprue, Whipple’s and Crohn’s can malabsorb folate and B12.
+* D.Latum is a competitor for B12 absorption. This entity is most commonly found in Scandinavia.
 ==References==