Lymphomatoid granulomatosis physical examination: Difference between revisions

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Physical examination of patients with Lymphomatoid granulomatosis is usually remarkable for Wheezing, Rales and Rhonchi
Physical examination of patients with Lymphomatoid granulomatosis is usually remarkable for Wheezing, Rales and Rhonchi
===Vital Signs===
===Vital Signs===
 
Patients may prestent with
*Fever
*Fever
==Skin===
===Skin===
In the case of cutaneous Lymphomatoid granulomatosis patients can present with following:
In the case of cutaneous Lymphomatoid granulomatosis patients can present with following:
*[[Rash|Erythematous rash]]<ref name="pmid27051739">{{cite journal| author=Shaigany S, Weitz NA, Husain S, Geskin L, Grossman ME| title=A case of lymphomatoid granulomatosis presenting with cutaneous lesions. | journal=JAAD Case Rep | year= 2015 | volume= 1 | issue= 4 | pages= 234-7 | pmid=27051739 | doi=10.1016/j.jdcr.2015.05.008 | pmc=4808726 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27051739  }} </ref>
*[[Rash|Erythematous rash]]<ref name="pmid27051739">{{cite journal| author=Shaigany S, Weitz NA, Husain S, Geskin L, Grossman ME| title=A case of lymphomatoid granulomatosis presenting with cutaneous lesions. | journal=JAAD Case Rep | year= 2015 | volume= 1 | issue= 4 | pages= 234-7 | pmid=27051739 | doi=10.1016/j.jdcr.2015.05.008 | pmc=4808726 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27051739  }} </ref>
Line 21: Line 21:
*[[Nodule (medicine)|Subcutaneous nodules]]<ref name="pmid27051739">{{cite journal| author=Shaigany S, Weitz NA, Husain S, Geskin L, Grossman ME| title=A case of lymphomatoid granulomatosis presenting with cutaneous lesions. | journal=JAAD Case Rep | year= 2015 | volume= 1 | issue= 4 | pages= 234-7 | pmid=27051739 | doi=10.1016/j.jdcr.2015.05.008 | pmc=4808726 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27051739  }} </ref><ref name="Prieto Herman ReinehrCorrêa Martins2017">{{cite journal|last1=Prieto Herman Reinehr|first1=Clarissa|last2=Corrêa Martins|first2=Carla|last3=Trein Cunha|first3=Vivian|last4=Elen Lira|first4=Franci|last5=Sprinz|first5=Eduardo|last6=Cartell|first6=André|last7=Bakos|first7=Renato Marchiori|title=Cutaneous human immunodeficiency virus (HIV)-associated lymphomatoid granulomatosis: complete regression following antiretroviral therapy|journal=International Journal of Dermatology|volume=56|issue=5|year=2017|pages=e100–e102|issn=00119059|doi=10.1111/ijd.13551}}</ref>
*[[Nodule (medicine)|Subcutaneous nodules]]<ref name="pmid27051739">{{cite journal| author=Shaigany S, Weitz NA, Husain S, Geskin L, Grossman ME| title=A case of lymphomatoid granulomatosis presenting with cutaneous lesions. | journal=JAAD Case Rep | year= 2015 | volume= 1 | issue= 4 | pages= 234-7 | pmid=27051739 | doi=10.1016/j.jdcr.2015.05.008 | pmc=4808726 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27051739  }} </ref><ref name="Prieto Herman ReinehrCorrêa Martins2017">{{cite journal|last1=Prieto Herman Reinehr|first1=Clarissa|last2=Corrêa Martins|first2=Carla|last3=Trein Cunha|first3=Vivian|last4=Elen Lira|first4=Franci|last5=Sprinz|first5=Eduardo|last6=Cartell|first6=André|last7=Bakos|first7=Renato Marchiori|title=Cutaneous human immunodeficiency virus (HIV)-associated lymphomatoid granulomatosis: complete regression following antiretroviral therapy|journal=International Journal of Dermatology|volume=56|issue=5|year=2017|pages=e100–e102|issn=00119059|doi=10.1111/ijd.13551}}</ref>
*[[Nodules|Larger ulcerated nodules]]<ref name="pmid27051739">{{cite journal| author=Shaigany S, Weitz NA, Husain S, Geskin L, Grossman ME| title=A case of lymphomatoid granulomatosis presenting with cutaneous lesions. | journal=JAAD Case Rep | year= 2015 | volume= 1 | issue= 4 | pages= 234-7 | pmid=27051739 | doi=10.1016/j.jdcr.2015.05.008 | pmc=4808726 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27051739  }} </ref><ref name="LeeNamuduri2018">{{cite journal|last1=Lee|first1=Lynette Y.|last2=Namuduri|first2=Rama|last3=Chan|first3=Michelle M. F.|last4=Quek|first4=Jeffrey K. S.|last5=Koh|first5=Mark J.-A.|title=Epstein-Barr virus positive diffuse large B-cell lymphoma presenting with vaginal sloughing and ulcerated skin nodule|journal=Journal of Cutaneous Pathology|volume=45|issue=2|year=2018|pages=162–166|issn=03036987|doi=10.1111/cup.13074}}</ref>
*[[Nodules|Larger ulcerated nodules]]<ref name="pmid27051739">{{cite journal| author=Shaigany S, Weitz NA, Husain S, Geskin L, Grossman ME| title=A case of lymphomatoid granulomatosis presenting with cutaneous lesions. | journal=JAAD Case Rep | year= 2015 | volume= 1 | issue= 4 | pages= 234-7 | pmid=27051739 | doi=10.1016/j.jdcr.2015.05.008 | pmc=4808726 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27051739  }} </ref><ref name="LeeNamuduri2018">{{cite journal|last1=Lee|first1=Lynette Y.|last2=Namuduri|first2=Rama|last3=Chan|first3=Michelle M. F.|last4=Quek|first4=Jeffrey K. S.|last5=Koh|first5=Mark J.-A.|title=Epstein-Barr virus positive diffuse large B-cell lymphoma presenting with vaginal sloughing and ulcerated skin nodule|journal=Journal of Cutaneous Pathology|volume=45|issue=2|year=2018|pages=162–166|issn=03036987|doi=10.1111/cup.13074}}</ref>
The differentials are the following [[Polymyositis and dermatomyositis|Dermatomyositis]], and [[Psoriasis]]<ref name="BertiFelicetti2018">{{cite journal|last1=Berti|first1=Alvise|last2=Felicetti|first2=Mara|last3=Peccatori|first3=Susanna|last4=Bortolotti|first4=Roberto|last5=Guella|first5=Anna|last6=Vivaldi|first6=Paolo|last7=Morelli|first7=Luca|last8=Barabareschi|first8=Mattia|last9=Paolazzi|first9=Giuseppe|title=EBV-induced lymphoproliferative disorders in rheumatic patients: A systematic review of the literature|journal=Joint Bone Spine|volume=85|issue=1|year=2018|pages=35–40|issn=1297319X|doi=10.1016/j.jbspin.2017.01.006}}</ref><ref name="pmid26966605">{{cite journal| author=O'Brien S, Schmidt P| title=Lymphomatoid Granulomatosis with Paraneoplastic Polymyositis: A Rare Malignancy with Rare Complication. | journal=Case Rep Rheumatol | year= 2016 | volume= 2016 | issue=  | pages= 8242597 | pmid=26966605 | doi=10.1155/2016/8242597 | pmc=4757691 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26966605  }} </ref>
===Lungs===
===Lungs===
Patients will most likely present with:
*Rhonchi
*Rhonchi
*[[Wheezing]] may be present
*[[Wheezing]] may be present
===Neuromuscular===
===Neuromuscular===
The case of CNS Lymphomatoid granulomatosis is rare, but patients that present with symptoms will have the following signs:
*[[Headache|Headaches]]<ref name="pmid21559262">{{cite journal| author=Castrale C, El Haggan W, Chapon F, Reman O, Lobbedez T, Ryckelynck JP et al.| title=Lymphomatoid granulomatosis treated successfully with rituximab in a renal transplant patient. | journal=J Transplant | year= 2011 | volume= 2011 | issue=  | pages= 865957 | pmid=21559262 | doi=10.1155/2011/865957 | pmc=3087939 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21559262  }} </ref>
*[[Headache|Headaches]]<ref name="pmid21559262">{{cite journal| author=Castrale C, El Haggan W, Chapon F, Reman O, Lobbedez T, Ryckelynck JP et al.| title=Lymphomatoid granulomatosis treated successfully with rituximab in a renal transplant patient. | journal=J Transplant | year= 2011 | volume= 2011 | issue=  | pages= 865957 | pmid=21559262 | doi=10.1155/2011/865957 | pmc=3087939 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21559262  }} </ref>
*[[Seizure|Seizures]]<ref name="LiuChen2014">{{cite journal|last1=Liu|first1=Hongli|last2=Chen|first2=Jing|last3=Yu|first3=Dandan|last4=Hu|first4=Jianli|title=Lymphomatoid granulomatosis involving the central nervous system: A case report and review of the literature|journal=Oncology Letters|volume=7|issue=6|year=2014|pages=1843–1846|issn=1792-1074|doi=10.3892/ol.2014.2002}}</ref>
*[[Seizure|Seizures]]<ref name="LiuChen2014">{{cite journal|last1=Liu|first1=Hongli|last2=Chen|first2=Jing|last3=Yu|first3=Dandan|last4=Hu|first4=Jianli|title=Lymphomatoid granulomatosis involving the central nervous system: A case report and review of the literature|journal=Oncology Letters|volume=7|issue=6|year=2014|pages=1843–1846|issn=1792-1074|doi=10.3892/ol.2014.2002}}</ref>

Revision as of 15:31, 12 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Common physical examination findings of Lymomatoid granulomatosis include Wheezing, Rales and Rhonchi

Physical Examination

Physical examination of patients with Lymphomatoid granulomatosis is usually remarkable for Wheezing, Rales and Rhonchi

Vital Signs

Patients may prestent with

  • Fever

Skin

In the case of cutaneous Lymphomatoid granulomatosis patients can present with following:

Lungs

Patients will most likely present with:

Neuromuscular

The case of CNS Lymphomatoid granulomatosis is rare, but patients that present with symptoms will have the following signs:

References

  1. ↑ 1.0 1.1 1.2 1.3 Shaigany S, Weitz NA, Husain S, Geskin L, Grossman ME (2015). "A case of lymphomatoid granulomatosis presenting with cutaneous lesions". JAAD Case Rep. 1 (4): 234–7. doi:10.1016/j.jdcr.2015.05.008. PMC 4808726. PMID 27051739.
  2. ↑ Carlson, Keith C. (1991). "Cutaneous Signs of Lymphomatoid Granulomatosis". Archives of Dermatology. 127 (11): 1693. doi:10.1001/archderm.1991.01680100093011. ISSN 0003-987X.
  3. ↑ Minars, Norman (1975). "Lymphomatoid Granulomatosis of the Skin". Archives of Dermatology. 111 (4): 493. doi:10.1001/archderm.1975.01630160083009. ISSN 0003-987X.
  4. ↑ Rysgaard, Carolyn D.; Stone, Mary Seabury (2015). "Lymphomatoid granulomatosis presenting with cutaneous involvement: a case report and review of the literature". Journal of Cutaneous Pathology. 42 (3): 188–193. doi:10.1111/cup.12402. ISSN 0303-6987.
  5. ↑ Prieto Herman Reinehr, Clarissa; Corrêa Martins, Carla; Trein Cunha, Vivian; Elen Lira, Franci; Sprinz, Eduardo; Cartell, André; Bakos, Renato Marchiori (2017). "Cutaneous human immunodeficiency virus (HIV)-associated lymphomatoid granulomatosis: complete regression following antiretroviral therapy". International Journal of Dermatology. 56 (5): e100–e102. doi:10.1111/ijd.13551. ISSN 0011-9059.
  6. ↑ Lee, Lynette Y.; Namuduri, Rama; Chan, Michelle M. F.; Quek, Jeffrey K. S.; Koh, Mark J.-A. (2018). "Epstein-Barr virus positive diffuse large B-cell lymphoma presenting with vaginal sloughing and ulcerated skin nodule". Journal of Cutaneous Pathology. 45 (2): 162–166. doi:10.1111/cup.13074. ISSN 0303-6987.
  7. ↑ Castrale C, El Haggan W, Chapon F, Reman O, Lobbedez T, Ryckelynck JP; et al. (2011). "Lymphomatoid granulomatosis treated successfully with rituximab in a renal transplant patient". J Transplant. 2011: 865957. doi:10.1155/2011/865957. PMC 3087939. PMID 21559262.
  8. ↑ Liu, Hongli; Chen, Jing; Yu, Dandan; Hu, Jianli (2014). "Lymphomatoid granulomatosis involving the central nervous system: A case report and review of the literature". Oncology Letters. 7 (6): 1843–1846. doi:10.3892/ol.2014.2002. ISSN 1792-1074.
  9. ↑ Patsalides, Athos D.; Atac, Gokce; Hedge, Upendra; Janik, John; Grant, Nicole; Jaffe, Elaine S.; Dwyer, Andrew; Patronas, Nicholas J.; Wilson, Wyndham H. (2005). "Lymphomatoid Granulomatosis: Abnormalities of the Brain at MR Imaging". Radiology. 237 (1): 265–273. doi:10.1148/radiol.2371041087. ISSN 0033-8419.
  10. ↑ Cargini, Pasqualino; Civica, Maria; Sollima, Laura; Di Cola, Emanuela; Pontecorvi, Emanuele; Cutilli, Tommaso (2014). "Oral lymphomatoid granulomatosis, the first sign of a 'rare disease': a case report". Journal of Medical Case Reports. 8 (1). doi:10.1186/1752-1947-8-152. ISSN 1752-1947.

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