Lisch nodule screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Swathi Venkatesan, M.B.B.S.[2]

Lisch Nodule Screening

• Lisch Nodules are not regularly screened, they’re usually detected when other signs and symptoms of neurofibromatosis appear.
• However, Lisch nodules are seen in 95% of children with NF1 by age 20
• They can often be seen with no magnification, especially in adults, who usually have multiple, bilateral nodules
• A slit-lamp examination, however, is required to distinguish them from nevi on the iris, which are flat or minimally elevated, densely pigmented lesions with blurred margins.

References

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