Lisch nodule screening: Difference between revisions
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==Lisch Nodule Screening== | ==Lisch Nodule Screening== | ||
*Lisch Nodules are not regularly screened, they’re usually detected when other signs and symptoms of neurofibromatosis appear. | *Lisch Nodules are not regularly screened, they’re usually detected when other signs and symptoms of neurofibromatosis appear. <ref name="FernerHuson2006">{{cite journal|last1=Ferner|first1=R. E|last2=Huson|first2=S. M|last3=Thomas|first3=N.|last4=Moss|first4=C.|last5=Willshaw|first5=H.|last6=Evans|first6=D G.|last7=Upadhyaya|first7=M.|last8=Towers|first8=R.|last9=Gleeson|first9=M.|last10=Steiger|first10=C.|last11=Kirby|first11=A.|title=Guidelines for the diagnosis and management of individuals with neurofibromatosis 1|journal=Journal of Medical Genetics|volume=44|issue=2|year=2006|pages=81–88|issn=1468-6244|doi=10.1136/jmg.2006.045906}}</ref> | ||
*However, Lisch nodules are seen in 95% of children with NF1 by age 20 | *However, Lisch nodules are seen in 95% of children with NF1 by age 20 | ||
*They can often be seen with no magnification, especially in adults, who usually have multiple, bilateral nodules | *They can often be seen with no magnification, especially in adults, who usually have multiple, bilateral nodules | ||
Latest revision as of 12:17, 20 June 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Swathi Venkatesan, M.B.B.S.[2]
Lisch Nodule Screening
- Lisch Nodules are not regularly screened, they’re usually detected when other signs and symptoms of neurofibromatosis appear. [1]
- However, Lisch nodules are seen in 95% of children with NF1 by age 20
- They can often be seen with no magnification, especially in adults, who usually have multiple, bilateral nodules
- A slit-lamp examination, however, is required to distinguish them from nevi on the iris, which are flat or minimally elevated, densely pigmented lesions with blurred margins.
References
- ↑ Ferner, R. E; Huson, S. M; Thomas, N.; Moss, C.; Willshaw, H.; Evans, D G.; Upadhyaya, M.; Towers, R.; Gleeson, M.; Steiger, C.; Kirby, A. (2006). "Guidelines for the diagnosis and management of individuals with neurofibromatosis 1". Journal of Medical Genetics. 44 (2): 81–88. doi:10.1136/jmg.2006.045906. ISSN 1468-6244.