Lisch nodule epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Swathi Venkatesan, M.B.B.S.[2]

Epidemiology & Demographics

  • Lisch nodules are predominantly visible in children usually after the age of six years.[1]
  • Lisch Nodule incidence in NF1 increases with age and their prevalence raises by about 10% per year of life, up to age 9.
  • Lisch nodules are found in 93% of adults with NF-1 but have not been described in NF-2.
  • Lisch Nodules may be found in a limited number of individuals without NF.[2]

References

  1. Maharaj, A; Singh,, VRS; Lalchan, SA (2014). "Lisch and the Importance of His Nodules". West Indian Medical Journal. doi:10.7727/wimj.2013.323. ISSN 0043-3144.
  2. Greene, Carol L; Male, Wendy S; Coleman, Shelley H; Ohrliok, Martin E; Gordon, Robert A (1987). "LISCH NODULES IN AN UNSELECTED POPULATION: PREVALENCE AND USEFULNESS AS INDICATION OF NEUROFIBROMATOSIS". Pediatric Research. 21 (4): 227A–227A. doi:10.1203/00006450-198704010-00368. ISSN 0031-3998.


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