Leptospirosis: Difference between revisions

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{{DiseaseDisorder infobox |
  Name        = Leptospirosis |
  Image      = Lepto-klein.JPG |
  Caption    = Leptospirose magnified 200 times with dark-field microscope |
  DiseasesDB  = 7403 |
  ICD10      = {{ICD10|A|27| |a|20}} |
  ICD9
  OMIM          = 607948 |
  MedlinePlus    = 001376 |
  eMedicineSubj  = med |
  eMedicineTopic = 1283 |
  eMedicine_mult = {{eMedicine2|emerg|856}} {{eMedicine2|ped|1298}} |
  MeshName      = Leptospirosis |
  MeshNumber    = C01.252.400.511 |
}}
__NOTOC__
__NOTOC__
{{Leptospirosis}}
{{Leptospirosis}}
{{CMG}};{{AE}}{{VSKP}}
{{About1|Leptospira}}
{{About1|Leptospira}}
'''For patient information on this page, click [[Leptospirosis (patient information)|here]]'''  
'''For patient information on this page, click [[Leptospirosis (patient information)|here]]'''  


{{CMG}}
{{SK}} Cane cutter's fever; Harvest fever; Infection due to Leptospira; Japanese autumnal fever; Queensland fever; Rice-field worker's disease; Seven day fever; Spirochaetal jaundice; Mud fever; Swamp fever; Cane field fever; Fort Bragg fever; Tibial fever; Haemorrhagic jaundice; Spirochetosis; Canicola fever; Rat Catcher’s yellows disease; Swineherds disease
 
{{SK}} Cane cutter's fever; Harvest fever; Infection due to Leptospira; Japanese autumnal fever; Queensland fever; Rice-field worker's disease; Seven day fever; Spirochaetal jaundice; Spirochetal jaundice


==[[Leptospirosis overview|Overview]]==
==[[Leptospirosis overview|Overview]]==
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==Treatment==
==Treatment==
[[Leptospirosis medical therapy|Medical Therapy]] | [[Leptospirosis primary prevention|Primary Prevention]] | [[Leptospirosis secondary prevention|Secondary Prevention]] | [[Leptospirosis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Leptospirosis future or investigational therapies|Future or Investigational Therapies]]
[[Leptospirosis medical therapy|Medical Therapy]] | [[Leptospirosis primary prevention|Primary Prevention]] | [[Leptospirosis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Leptospirosis future or investigational therapies|Future or Investigational Therapies]]


==Case Studies==
==Case Studies==
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==Related Chapters==
==Related Chapters==
* [[Leptospira]]
* [[Leptospira]]
==Research==
Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis. 2003 Dec;3(12):757-71
Bharti AR, Nally JE, Ricaldi JN, Matthias MA, Diaz MM, Lovett MA, Levett PN, Gilman RH, Willig MR, Gotuzzo E, Vinetz JM; Peru-United States Leptospirosis Consortium.
In the past decade, leptospirosis has emerged as a globally important infectious disease. It occurs in urban environments of industrialised and developing countries, as well as in rural regions worldwide. Mortality remains significant, related both to delays in diagnosis due to lack of infrastructure and adequate clinical suspicion, and to other poorly understood reasons that may include inherent pathogenicity of some leptospiral strains or genetically determined host immunopathological responses. Pulmonary haemorrhage is recognised increasingly as a major, often lethal, manifestation of leptospirosis, the pathogenesis of which remains unclear. The completion of the genome sequence of Leptospira interrogans serovar lai, and other continuing leptospiral genome sequencing projects, promise to guide future work on the disease. Mainstays of treatment are still tetracyclines and beta-lactam/cephalosporins. No vaccine is available. Prevention is largely dependent on sanitation measures that may be difficult to implement, especially in developing countries.
In a study of 38 dogs diagnosed and properly treated for leptospirosis published in the February 2000 issue of the ''Journal of the American Veterinary Association'', the survival rate for the dialysis patients was slightly higher than the ones not put on dialysis, but both were in the 85% range (plus or minus). Of the dogs in this study that did not die, most recovered adequate kidney function, although one had chronic renal problems.
==See also==
* Marine Mammal Center


==External links==
==External links==
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*[http://www.leptoinfo.com leptoinfo.com - A website for Dog Owners and Veterinary Professionals dedicated to sharing information on Leptospirosis in Canada]
*[http://www.leptoinfo.com leptoinfo.com - A website for Dog Owners and Veterinary Professionals dedicated to sharing information on Leptospirosis in Canada]


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Latest revision as of 22:29, 29 July 2020

Leptospirosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Leptospirosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Other Imaging Findings

Treatment

Medical Therapy

Surgery

Primary Prevention

Future or Investigational Therapies

Case Studies

Case #1

Leptospirosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Leptospirosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Leptospirosis

CDC on Leptospirosis

Leptospirosis in the news

Blogs on Leptospirosis

Directions to Hospitals Treating Leptospirosis

Risk calculators and risk factors for Leptospirosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Venkata Sivakrishna Kumar Pulivarthi M.B.B.S [2]

This page is about clinical aspects of the disease.  For microbiologic aspects of the causative organism(s), see Leptospira.

For patient information on this page, click here

Synonyms and keywords: Cane cutter's fever; Harvest fever; Infection due to Leptospira; Japanese autumnal fever; Queensland fever; Rice-field worker's disease; Seven day fever; Spirochaetal jaundice; Mud fever; Swamp fever; Cane field fever; Fort Bragg fever; Tibial fever; Haemorrhagic jaundice; Spirochetosis; Canicola fever; Rat Catcher’s yellows disease; Swineherds disease

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Leptospirosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Imaging Findings | Other Diagnostic Studies | Leptospirosis criteria

Treatment

Medical Therapy | Primary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case#1

Related Chapters

External links


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