Leiomyosarcoma physical examination

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Overview

Patients with Leiomyosarcoma generally appear weak.Physical examination findings depends upon the site of the involvement,size and metastasis.Physical Examination findings may include weight loss, abdominal mass, Distension,Ascites, rectal bleeding and vaginal bleeding

Physical Examination

Physical examination findings depends upon the site of the involvement,size and metastasis.

Appearance of the Patient

• Patients with Leiomyosarcoma are generally weak due to weight loss.

Vital Signs

• Low Grade Fever

Skin

• Jaundice may appear if the tumor develops in the inferior vena cava in the supra-hepatic segment
• Pallor

Neck

• Lymphadenopathy

Lungs

• Dyspnea and chest pain in case of Leiomyosarcoma of the Pulmonary artert

Abdomen

• Non tender Abdominal mass
• Abdominal distension,hepatomegaly and ascites in case of Leiomyosarcoma of the inferior vena cava

Rectum

• Blood on rectal Examination

Genitourinary

• Vaginal bleeding and discharge in case of uterine Leiomyosarcoma.

Extremities

Lower extremity edema if the tumors that arise in the inferior vena cava below the liver

Neuromuscular

• paresthesia due to the compression of the neurovascular bundle by the enlarging mass

Paraneoplasic Syndrome manifestations

Rarely, Leiomyosarcoma presents with paraneoplastic hypoglycemia, which is usually secondary to the tumour production of insulin like growth factor-2

References

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