Leiomyosarcoma historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Overview

Soft tissue sarcoma derived their name from the greek term for a fleshy lump. Around 460 B.C, Hippocrates recognized soft tissue tumors in the arm and thigh in older people and recommended the removal by knife as therapy. In 200 C.E., a greek physician named Galen suggested that these lumps were cancerous tumors. The exact cause of leiomyosarcoma still is not well understood because of rarety of disease.

Historical Perspective

  • Soft tissue sarcoma derived their name from the Greek term for a fleshy lump.[1]
  • Around 460 B.C, Hippocrates recognized soft tissue tumors in the arm and thigh in older people and recommended the removal by knife as therapy. [2]
  • Around 200 C.E., a greek physician named Galen suggested that these lumps were cancerous tumors.[3]
  • In 1809, an Edinburg surgeon, Wardrop describes the first illustration of amputation and used the term "soft cancer".[4]
  • In 1816, Charles Bell, used the term soft tissue sarcoma to differentiate it form carcinoma.[5]
  • In 1804, Abernethy describes the first classification of the sarcoma.[6]
  • In 1932, Stout published a litreature on the pathology and treatment of sarcoma.[7]
  • In 1982, Rosenberg evaluated limb-sparing surgery with adjuvant radiotherapy compared with major amputation.[8]

References

  1. Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  2. Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  3. Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  4. Erstad, Derek J.; Raut, Chandrajit P. (2017). "Amputation for Sarcoma: Revisiting a 19th Century Treatment in the 21st Century". Annals of Surgical Oncology. 25 (2): 351–353. doi:10.1245/s10434-017-6243-2. ISSN 1068-9265.
  5. Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  6. Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  7. Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  8. Rosenberg SA, Tepper J, Glatstein E, Costa J, Baker A, Brennan M, DeMoss EV, Seipp C, Sindelar WF, Sugarbaker P, Wesley R (September 1982). "The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy". Ann. Surg. 196 (3): 305–15. PMC 1352604. PMID 7114936.

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