Leiomyosarcoma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Rekha, M.D.

Overview

The majority of patients with leiomyosarcoma remain asymptomatic for decades. General symptoms associated with cancer may occur including fatigue, fever, weight loss, a general feeling of ill health (malaise), and nausea and vomiting, GI bleeding, metastasis.

History and Symptoms

The symptoms of leiomyosarcoma depend on the location of the tumor. For the tumors always develop in gastrointestinal tract and uterus, usual symptoms are the following.

  • A new lump or a lump that is growing anywhere on your body[1][2]
  • Pelvic pain in Uterine Leiomyosarcoma
  • Dysphagia in Esophageal Leiomyosarcoma[3]
  • Black, tarry stools or rectal bleeding in Rectal Leiomyosarcoma[4]

References

  1. Quade BJ (1995) Pathology, cytogenetics and molecular biology of uterine leiomyomas and other smooth muscle lesions. Curr Opin Obstet Gynecol 7 (1):35-42. PMID: 7742513
  2. Hartman DS, Hayes WS, Choyke PL, Tibbetts GP (1992) From the archives of the AFIP. Leiomyosarcoma of the retroperitoneum and inferior vena cava: radiologic-pathologic correlation. Radiographics 12 (6):1203-20. DOI:10.1148/radiographics.12.6.1439022 PMID: 1439022
  3. Zhang BH, Zhang HT, Wang YG (2014) Esophageal leiomyosarcoma: clinical analysis and surgical treatment of 12 cases. Dis Esophagus 27 (6):547-51. DOI:10.1111/j.1442-2050.2012.01444.x PMID: 23163522
  4. Jideh B, Yang T, Turner I (2017) Rectal Bleeding Due to Leiomyosarcoma. Clin Gastroenterol Hepatol 15 (1):e1-e2. DOI:10.1016/j.cgh.2016.08.008 PMID: 27530097
  5. Liao Q, Wang J, Han J (2001) [Clinical and pathological analysis on 106 cases with uterine sarcoma.] Zhonghua Fu Chan Ke Za Zhi 36 (2):104-7. PMID: 11783345


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