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{{Leiomyosarcoma}}
{{Leiomyosarcoma}}


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==Overview==
==Overview==
* Soft tissue sarcoma derived their name from the Greek term for a fleshy excrescences.As early as Galen(130-200C.E.),it was suggested that they were a cancerous tumor.Early reports of myxoid liposarcoma by Severinius(1580-1637) and retroperitoneal sarcoma by Morgagni (1682-1771) have been recorded.An Edinburg surgeon, Wardrop( 1782-1869),who studied in Vienna,describes the term soft cancer.Charles Bell ( 1772-1842) ,in his book Surgical Observations, published in 1816, has been credited with the utilization of the term soft tissue sarcoma to differentiate it form carcinoma.In 1804, Abernethy describes the first classification of the sarcoma.In1932 Stout (1885-1967) published a seminal monograph on the pathology and treatment of sarcoma.Ewing was one of the first to list benign and malignant counterparts of tumors arising in soft tissues.
Soft tissue sarcoma derived their name from the greek term for a fleshy lump. Around 460 B.C, Hippocrates recognized soft tissue tumors in the arm and thigh in older people and recommended the removal by knife as therapy. In 200 C.E., a greek physician named Galen suggested that these lumps were cancerous tumors. The exact cause of leiomyosarcoma still is not well understood because of rarety of disease.  


==Historical Perspective==
==Historical Perspective==
 
:*[[Soft tissue]] [[sarcoma]] derived their name from the Greek term for a fleshy lump.<ref name="Hajdu20074">{{cite journal|last1=Hajdu|first1=Steven I.|title=Soft tissue sarcomas|journal=Cancer|volume=109|issue=9|year=2007|pages=1697–1704|issn=0008543X|doi=10.1002/cncr.22608}}</ref>
===Discovery===
:*Around 460 B.C, Hippocrates recognized [[soft tissue]] tumors in the arm and thigh in older people and recommended the removal by knife as therapy. <ref name="Hajdu20073">{{cite journal|last1=Hajdu|first1=Steven I.|title=Soft tissue sarcomas|journal=Cancer|volume=109|issue=9|year=2007|pages=1697–1704|issn=0008543X|doi=10.1002/cncr.22608}}</ref>
*Soft tissue sarcoma derived their name from the Greek term for a fleshy excrescence.<ref name="BrennanAntonescu2016">{{cite book|author1=Murray F. Brennan|author2=Cristina R. Antonescu|author3=Kaled M. Alektiar|coauthors=Robert G. Maki|title=Management of Soft Tissue Sarcoma|url=https://books.google.com/books?id=GVK7DQAAQBAJ|date=15 December 2016|publisher=Springer|isbn=978-3-319-41906-0}}</ref>
:*Around 200 C.E., a greek physician named Galen suggested that these lumps were cancerous tumors.<ref name="Hajdu20075">{{cite journal|last1=Hajdu|first1=Steven I.|title=Soft tissue sarcomas|journal=Cancer|volume=109|issue=9|year=2007|pages=1697–1704|issn=0008543X|doi=10.1002/cncr.22608}}</ref>
*As early as Galen(130-200C.E.),it was suggested that they were a cancerous tumor.
:*In 1809, an Edinburg surgeon, Wardrop describes the first illustration of [[amputation]] and used the term "soft [[cancer]]".<ref name="ErstadRaut2017">{{cite journal|last1=Erstad|first1=Derek J.|last2=Raut|first2=Chandrajit P.|title=Amputation for Sarcoma: Revisiting a 19th Century Treatment in the 21st Century|journal=Annals of Surgical Oncology|volume=25|issue=2|year=2017|pages=351–353|issn=1068-9265|doi=10.1245/s10434-017-6243-2}}</ref>
*Early reports of myxoid liposarcoma by Severinius(1580-1637) and retroperitoneal sarcoma by Morgagni (1682-1771) have been recorded.  
:*In 1816, Charles Bell, used the term soft tissue [[sarcoma]] to differentiate it form [[carcinoma]].<ref name="Hajdu20076">{{cite journal|last1=Hajdu|first1=Steven I.|title=Soft tissue sarcomas|journal=Cancer|volume=109|issue=9|year=2007|pages=1697–1704|issn=0008543X|doi=10.1002/cncr.22608}}</ref>
*An Edinburg surgeon, Wardrop( 1782-1869),who studied in Vienna,describes the term soft cancer.
:*In 1804, Abernethy describes the first classification of the sarcoma.<ref name="Hajdu20072">{{cite journal|last1=Hajdu|first1=Steven I.|title=Soft tissue sarcomas|journal=Cancer|volume=109|issue=9|year=2007|pages=1697–1704|issn=0008543X|doi=10.1002/cncr.22608}}</ref>
*Charles Bell ( 1772-1842) ,in his book Surgical Observations, published in 1816, has been credited with the utilization of the term soft tissue sarcoma to differentiate it form carcinoma.
:*In 1932, Stout published a litreature on the [[pathology]] and treatment of sarcoma.<ref name="Hajdu2007">{{cite journal|last1=Hajdu|first1=Steven I.|title=Soft tissue sarcomas|journal=Cancer|volume=109|issue=9|year=2007|pages=1697–1704|issn=0008543X|doi=10.1002/cncr.22608}}</ref>
*In 1804, Abernethy describes the first classification of the sarcoma.
:*In 1982, Rosenberg evaluated limb-sparing surgery with adjuvant [[radiotherapy]] compared with major [[amputation]].<ref name="pmid7114936">{{cite journal |vauthors=Rosenberg SA, Tepper J, Glatstein E, Costa J, Baker A, Brennan M, DeMoss EV, Seipp C, Sindelar WF, Sugarbaker P, Wesley R |title=The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy |journal=Ann. Surg. |volume=196 |issue=3 |pages=305–15 |date=September 1982 |pmid=7114936 |pmc=1352604 |doi= |url=http://Insights.ovid.com/pubmed?pmid=7114936}}</ref>
*In 1932 Stout( 1885-1967) published a seminal monograph on the pathology and treatment of sarcoma.
*Ewing was one of the first to list benign and malignant counterparts of tumors arising in soft tissues.
*In 1944, the first description of liposarcoma has been attributed to Stout, also at Memorial Sloan Kettering, as was the description with Ackerman of Leiomyosarcoma of soft tissue in 1947.
*In 1897, Griffon et al reported the first case of LMS of the gallbladder.<ref name="pmid20187695">García Marín A, Bernardos García L, Martín Gil J, Serralta de Colsa D, Turégano Fuentes F (2010) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=20187695 Primary leiomyosarcoma of the gallbladder.] ''Rev Esp Enferm Dig'' 102 (1):67-8. PMID: [https://pubmed.gov/20187695 20187695]</ref>
*Primary bone Leiomyosarcoma was first described in 1965 <ref name="pmid29137065">Recine F, Bongiovanni A, Casadei R, Pieri F, Riva N, De Vita A et al. (2017) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=29137065 Primary leiomyosarcoma of the bone: a case report and a review of the literature.] ''Medicine (Baltimore)'' 96 (45):e8545. [http://dx.doi.org/10.1097/MD.0000000000008545 DOI:10.1097/MD.0000000000008545] PMID: [https://pubmed.gov/29137065 29137065]</ref>by Evans and Sanerkin.<ref name="pmid28248883">Yang Y, Ma L, Li L, Liu H (2017) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=28248883 Primary leiomyosarcoma of the spine: A case report and literature review.] ''Medicine (Baltimore)'' 96 (9):e6227. [http://dx.doi.org/10.1097/MD.0000000000006227 DOI:10.1097/MD.0000000000006227] PMID: [https://pubmed.gov/28248883 28248883]</ref>  
 


==References==
==References==

Latest revision as of 16:45, 2 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Overview

Soft tissue sarcoma derived their name from the greek term for a fleshy lump. Around 460 B.C, Hippocrates recognized soft tissue tumors in the arm and thigh in older people and recommended the removal by knife as therapy. In 200 C.E., a greek physician named Galen suggested that these lumps were cancerous tumors. The exact cause of leiomyosarcoma still is not well understood because of rarety of disease.

Historical Perspective

  • Soft tissue sarcoma derived their name from the Greek term for a fleshy lump.[1]
  • Around 460 B.C, Hippocrates recognized soft tissue tumors in the arm and thigh in older people and recommended the removal by knife as therapy. [2]
  • Around 200 C.E., a greek physician named Galen suggested that these lumps were cancerous tumors.[3]
  • In 1809, an Edinburg surgeon, Wardrop describes the first illustration of amputation and used the term "soft cancer".[4]
  • In 1816, Charles Bell, used the term soft tissue sarcoma to differentiate it form carcinoma.[5]
  • In 1804, Abernethy describes the first classification of the sarcoma.[6]
  • In 1932, Stout published a litreature on the pathology and treatment of sarcoma.[7]
  • In 1982, Rosenberg evaluated limb-sparing surgery with adjuvant radiotherapy compared with major amputation.[8]

References

  1. ↑ Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  2. ↑ Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  3. ↑ Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  4. ↑ Erstad, Derek J.; Raut, Chandrajit P. (2017). "Amputation for Sarcoma: Revisiting a 19th Century Treatment in the 21st Century". Annals of Surgical Oncology. 25 (2): 351–353. doi:10.1245/s10434-017-6243-2. ISSN 1068-9265.
  5. ↑ Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  6. ↑ Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  7. ↑ Hajdu, Steven I. (2007). "Soft tissue sarcomas". Cancer. 109 (9): 1697–1704. doi:10.1002/cncr.22608. ISSN 0008-543X.
  8. ↑ Rosenberg SA, Tepper J, Glatstein E, Costa J, Baker A, Brennan M, DeMoss EV, Seipp C, Sindelar WF, Sugarbaker P, Wesley R (September 1982). "The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy". Ann. Surg. 196 (3): 305–15. PMC 1352604. PMID 7114936.

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