Legionellosis other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Other Diagnostic Studies

Sampling

Bronchoalveolar Lavage

Bronchoalveolar lavage (BAL) fluids can be submitted for cultures and PCR in pediatric patients.

Thoracocentesis

Thoracocentesis may be performed to obtain pleural fluid samples in the presence of significant effusion.

Assay

Polymerase Chain Reaction

Polymerase chain reaction (PCR) is used to detect DNA of Legionella in urine, blood, pleural fluid, or bronchoalveolar lavage samples. PCR is an alternative tool for rapid Legionella detection in environmental water. The detection rate of Legionella DNA by qualitative PCR is usually high, at > 90% of positive samples.

References