Infectious colitis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qasim Salau, M.B.B.S., FMCPaed [2]

Overview

Diagnostic laboratory tests to identify the pathogen causing infectious colitis include stool and blood culture, serology, or polymerase chain reaction (PCR). Non specific laboratory findings in infectious colitis are also done and helpful to rule out development of complications.

Laboratory Findings

The table below displays nonspecific laboratory abnormalities associated with Infectious colitis, including:[1][2][3][4][5]

Laboratory findings
Test Findings
Complete Blood Count
Electrolytes
Inflammatory Markers
  • CRP is often elevated
  • ESR may be elevated
Blood cultures
  • Indicated in the presence of prolonged or recurrent fever
  • May reveal presence of the bacteria, in case of bacteremia
  • Commonly positive in endovascular infections
Urinalysis

References

  1. "Diarrhoea and Vomiting Caused by Gastroenteritis".
  2. Agarwal R, Afzalpurkar R, Fordtran JS (1994). "Pathophysiology of potassium absorption and secretion by the human intestine". Gastroenterology. 107 (2): 548–71. PMID 8039632.
  3. Wang F, Butler T, Rabbani GH, Jones PK (1986). "The acidosis of cholera. Contributions of hyperproteinemia, lactic acidemia, and hyperphosphatemia to an increased serum anion gap". N Engl J Med. 315 (25): 1591–5. doi:10.1056/NEJM198612183152506. PMID 3785323.
  4. Welbourne T, Weber M, Bank N (1972). "The effect of glutamine administration on urinary ammonium excretion in normal subjects and patients with renal disease". J Clin Invest. 51 (7): 1852–60. doi:10.1172/JCI106987. PMC 292333. PMID 4555786.
  5. Batlle DC, von Riotte A, Schlueter W (1987). "Urinary sodium in the evaluation of hyperchloremic metabolic acidosis". N Engl J Med. 316 (3): 140–4. doi:10.1056/NEJM198701153160305. PMID 3796685.

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