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Integrins are integral membrane proteins composed of an alpha chain and a beta chain, and are known to participate in cell adhesion as well as cell-surface mediated signalling. The I-domain containing alpha 10 combines with the integrin beta 1 chain (ITGB1) to form a novel collagen type II-binding integrin expressed in cartilage tissue.[1]
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Wenke AK, Rothhammer T, Moser M, Bosserhoff AK (2006). "Regulation of integrin alpha10 expression in chondrocytes by the transcription factors AP-2epsilon and Ets-1". Biochem. Biophys. Res. Commun. 345 (1): 495–501. doi:10.1016/j.bbrc.2006.04.123. PMID16684505.