Hypopharyngeal cancer epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Epidemiology and Demographics
Squamous cell carcinomas account for approximately 95% of all primary tumours of the hypopharynx 6.
The epidemiology of hypopharyngeal SCC is essentially the same as that of othersquamous cell carcinomas of the aerodigestive tract of the head and neck, and is typically encountered in patients with a long history of smoking tobacco and alcohol consumption 1-2. As such they are more common in males, with perhaps the exception of posterior cricoid tumours which may be more common in women (especially of northern Europe) with Plummer-Vinson syndrome 2,6.
Human papilloma virus may also play a role, although it is isolated in far fewer patients with hypopharyngeal SCC (16%) compared to oropharyngeal SCC 1-2. See squamous cell carcinomas of the aerodigestive tract of the head and neck for a general discussion.
Hypopharyngeal carcinoma is relatively uncommon representing only 10% of all proximal aerodigestive track malignancies 2.
- Most cancers of the throat develop in adults older than 50.
- Men are 10 times more likely than women to develop throat cancers.