Hirschsprung's disease natural history, complications and prognosis: Difference between revisions
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{{Hirschsprung's disease}} | {{Hirschsprung's disease}} | ||
{{CMG}};{{AE}}{{AY}} | {{CMG}}; {{AE}} {{AY}} | ||
==Overview== | ==Overview== | ||
If left untreated, Hirschsprung disease can lead to [[enterocolitis]] and death. Common complications include [[enterocolitis]], [[intestinal perforation]] and [[short bowel syndrome]]. | If left untreated, Hirschsprung's disease can lead to [[enterocolitis]] and even death. Common complications include [[enterocolitis]], [[intestinal perforation]], and [[short bowel syndrome]]. Using appropriate surgical interventions, [[Mortality rate|mortality rate]] drops significantly. | ||
==Natural history== | ==Natural history== | ||
If left untreated, Hirschsprung disease can lead to [[enterocolitis]] and death. | If left untreated, Hirschsprung's disease can lead to [[enterocolitis]] and even death. | ||
==Complications== | ==Complications== | ||
===Possible complications of surgery include=== | === Possible complications of disease include: === | ||
*Wound infection | * [[Inflammation]] and [[infection]] of the [[intestine]]s/[[colon]] ([[enterocolitis]]) | ||
*[[Anastomotic lesions| | * [[Intestinal perforation]] | ||
* [[Short bowel syndrome]] (which can lead to [[malnourishment]] and [[dehydration]])<ref name="pmid6712314">{{cite journal |vauthors=Ikeda K, Goto S |title=Diagnosis and treatment of Hirschsprung's disease in Japan. An analysis of 1628 patients |journal=Ann. Surg. |volume=199 |issue=4 |pages=400–5 |year=1984 |pmid=6712314 |pmc=1353357 |doi= |url=}}</ref> | |||
===Possible complications of reconstructive surgery include:=== | |||
*Wound [[infection]] | |||
*[[Anastomotic lesions|Anastomosis leakage]] | |||
*[[Intestinal obstruction]] | *[[Intestinal obstruction]] | ||
*[[Pelvic abscess]] | *[[Pelvic abscess]] | ||
*Chronic | *[[Chronic]] [[bowel obstruction]] symptoms | ||
*Chronic [[constipation]] or [[diarrhea]] | *[[Chronic]] [[constipation]] or [[diarrhea]]<ref name="pmid6712314">{{cite journal |vauthors=Ikeda K, Goto S |title=Diagnosis and treatment of Hirschsprung's disease in Japan. An analysis of 1628 patients |journal=Ann. Surg. |volume=199 |issue=4 |pages=400–5 |year=1984 |pmid=6712314 |pmc=1353357 |doi= |url=}}</ref> | ||
==Prognosis== | ==Prognosis== | ||
*Hirschsprung disease can lead to [[Mortality rate|mortality]] in up to 80% of cases. | *Hirschsprung's disease can lead to [[Mortality rate|mortality]] in up to 80% of cases. | ||
* | *Using appropriate surgical interventions, [[Mortality rate|mortality]] would drops to 30%. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Latest revision as of 14:59, 21 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
If left untreated, Hirschsprung's disease can lead to enterocolitis and even death. Common complications include enterocolitis, intestinal perforation, and short bowel syndrome. Using appropriate surgical interventions, mortality rate drops significantly.
Natural history
If left untreated, Hirschsprung's disease can lead to enterocolitis and even death.
Complications
Possible complications of disease include:
- Inflammation and infection of the intestines/colon (enterocolitis)
- Intestinal perforation
- Short bowel syndrome (which can lead to malnourishment and dehydration)[1]
Possible complications of reconstructive surgery include:
- Wound infection
- Anastomosis leakage
- Intestinal obstruction
- Pelvic abscess
- Chronic bowel obstruction symptoms
- Chronic constipation or diarrhea[1]
Prognosis
- Hirschsprung's disease can lead to mortality in up to 80% of cases.
- Using appropriate surgical interventions, mortality would drops to 30%.