Hirschsprung's disease history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]} ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Hirschsprung's disease is commonly diagnosed in the neonatal period. The cardinal symptoms of Hirschsprung's disease include abdominal distension, delayed passage of meconium (not occurring in the first 24 to 48 hours of life) and vomiting. [1][2]

History

  • Delayed passage of meconium (not occurring in the first 24 to 48 hours of life)
  • Ninety-four percent of Hirschsprung's disease cases are diagnosed before the patient reaches 5 years of age.
  • History of longstanding recurrent constipation, relieved by laxatives.
  • History of progressive abdominal distention, colicky pain or acute intestinal obstruction. [3]

Symptoms

The cardinal symptoms of Hirschsprung's disease are:

Other common symptoms that can be observed in patients with Hirschsprung's disease include

References

  1. Stanescu AL, Liszewski MC, Lee EY, Phillips GS (2017). "Neonatal Gastrointestinal Emergencies: Step-by-Step Approach". Radiol. Clin. North Am. 55 (4): 717–739. doi:10.1016/j.rcl.2017.02.010. PMID 28601177.
  2. Das K, Mohanty S (2017). "Hirschsprung Disease - Current Diagnosis and Management". Indian J Pediatr. doi:10.1007/s12098-017-2371-8. PMID 28600660.
  3. Guderian R, Vargas J (1986). "Duffy blood group distribution and the incidence of malaria in Ecuador". Trans. R. Soc. Trop. Med. Hyg. 80 (1): 162–3. PMID 3726979.