Hemophilia risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
The most potent risk factor in the development of hemophilia is the family history of hemophilia. Other risk factors include male sex and malignancies.
Risk Factors
- The most potent risk factor in the development of hemophilia is the family history of hemophilia.[1][2]
- Male sex is also a very common risk factor.[3]
- Current history of malignancy can also be considered a risk factor on account of the association between malignancies and acquired hemophilia.[4]
References
- ↑ Mannucci PM, Tuddenham EG (June 2001). "The hemophilias--from royal genes to gene therapy". N. Engl. J. Med. 344 (23): 1773–9. doi:10.1056/NEJM200106073442307. PMID 11396445.
- ↑ Ingram, G I (1976). "The history of haemophilia". Journal of Clinical Pathology. 29 (6): 469–479. doi:10.1136/jcp.29.6.469. ISSN 0021-9746.
- ↑ Di Michele DM, Gibb C, Lefkowitz JM, Ni Q, Gerber LM, Ganguly A (March 2014). "Severe and moderate haemophilia A and B in US females". Haemophilia. 20 (2): e136–43. doi:10.1111/hae.12364. PMID 24533955.
- ↑ Napolitano M, Siragusa S, Mancuso S, Kessler CM (January 2018). "Acquired haemophilia in cancer: A systematic and critical literature review". Haemophilia. 24 (1): 43–56. doi:10.1111/hae.13355. PMID 28960809.