Hemophilia risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
The most potent risk factor in the development of hemophilia is the family history of hemophilia. Other risk factors include male sex and malignancies. | The most potent risk factor in the development of hemophilia is the family history of hemophilia. Other [[Risk factor|risk factors]] include [[Male|male sex]] and [[Cancer|malignancies]]. | ||
==Risk Factors== | ==Risk Factors== | ||
*The most potent risk factor in the development of hemophilia is the family history of hemophilia.<ref name="pmid11396445">{{cite journal |vauthors=Mannucci PM, Tuddenham EG |title=The hemophilias--from royal genes to gene therapy |journal=N. Engl. J. Med. |volume=344 |issue=23 |pages=1773–9 |date=June 2001 |pmid=11396445 |doi=10.1056/NEJM200106073442307 |url=}}</ref><ref name="Ingram1976">{{cite journal|last1=Ingram|first1=G I|title=The history of haemophilia.|journal=Journal of Clinical Pathology|volume=29|issue=6|year=1976|pages=469–479|issn=0021-9746|doi=10.1136/jcp.29.6.469}}</ref> | *The most potent [[risk factor]] in the development of hemophilia is the [[family history]] of hemophilia.<ref name="pmid11396445">{{cite journal |vauthors=Mannucci PM, Tuddenham EG |title=The hemophilias--from royal genes to gene therapy |journal=N. Engl. J. Med. |volume=344 |issue=23 |pages=1773–9 |date=June 2001 |pmid=11396445 |doi=10.1056/NEJM200106073442307 |url=}}</ref><ref name="Ingram1976">{{cite journal|last1=Ingram|first1=G I|title=The history of haemophilia.|journal=Journal of Clinical Pathology|volume=29|issue=6|year=1976|pages=469–479|issn=0021-9746|doi=10.1136/jcp.29.6.469}}</ref> | ||
*Male sex is also a very common risk factor.<ref name="pmid24533955">{{cite journal |vauthors=Di Michele DM, Gibb C, Lefkowitz JM, Ni Q, Gerber LM, Ganguly A |title=Severe and moderate haemophilia A and B in US females |journal=Haemophilia |volume=20 |issue=2 |pages=e136–43 |date=March 2014 |pmid=24533955 |doi=10.1111/hae.12364 |url=}}</ref> | *Male sex is also a very common [[risk factor]].<ref name="pmid24533955">{{cite journal |vauthors=Di Michele DM, Gibb C, Lefkowitz JM, Ni Q, Gerber LM, Ganguly A |title=Severe and moderate haemophilia A and B in US females |journal=Haemophilia |volume=20 |issue=2 |pages=e136–43 |date=March 2014 |pmid=24533955 |doi=10.1111/hae.12364 |url=}}</ref> | ||
*Current history of malignancy can also be considered a risk factor on account of the association between malignancies and acquired hemophilia.<ref name="pmid28960809">{{cite journal |vauthors=Napolitano M, Siragusa S, Mancuso S, Kessler CM |title=Acquired haemophilia in cancer: A systematic and critical literature review |journal=Haemophilia |volume=24 |issue=1 |pages=43–56 |date=January 2018 |pmid=28960809 |doi=10.1111/hae.13355 |url=}}</ref> | *Current history of [[Cancer|malignancy]] can also be considered a [[risk factor]] on account of the association between [[Cancer|malignancies]] and acquired hemophilia.<ref name="pmid28960809">{{cite journal |vauthors=Napolitano M, Siragusa S, Mancuso S, Kessler CM |title=Acquired haemophilia in cancer: A systematic and critical literature review |journal=Haemophilia |volume=24 |issue=1 |pages=43–56 |date=January 2018 |pmid=28960809 |doi=10.1111/hae.13355 |url=}}</ref> | ||
==References== | ==References== | ||
Revision as of 18:36, 16 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
The most potent risk factor in the development of hemophilia is the family history of hemophilia. Other risk factors include male sex and malignancies.
Risk Factors
- The most potent risk factor in the development of hemophilia is the family history of hemophilia.[1][2]
- Male sex is also a very common risk factor.[3]
- Current history of malignancy can also be considered a risk factor on account of the association between malignancies and acquired hemophilia.[4]
References
- ↑ Mannucci PM, Tuddenham EG (June 2001). "The hemophilias--from royal genes to gene therapy". N. Engl. J. Med. 344 (23): 1773–9. doi:10.1056/NEJM200106073442307. PMID 11396445.
- ↑ Ingram, G I (1976). "The history of haemophilia". Journal of Clinical Pathology. 29 (6): 469–479. doi:10.1136/jcp.29.6.469. ISSN 0021-9746.
- ↑ Di Michele DM, Gibb C, Lefkowitz JM, Ni Q, Gerber LM, Ganguly A (March 2014). "Severe and moderate haemophilia A and B in US females". Haemophilia. 20 (2): e136–43. doi:10.1111/hae.12364. PMID 24533955.
- ↑ Napolitano M, Siragusa S, Mancuso S, Kessler CM (January 2018). "Acquired haemophilia in cancer: A systematic and critical literature review". Haemophilia. 24 (1): 43–56. doi:10.1111/hae.13355. PMID 28960809.