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The physical examination findings of hemolytic anemia reflect (1) red blood cell loss and (2) the release of hemoglobin and its breakdown productions into the circulation. Exam findings in hemolytic anemia include: | The physical examination findings of hemolytic anemia reflect (1) red blood cell loss and (2) the release of hemoglobin and its breakdown productions into the circulation. Exam findings in hemolytic anemia include: | ||
*[['''Jaundice | *[['''Jaundice''']]: This is due to Increased serum [[bilirubin]] levels in [[blood]]. Bilirubin is a breakdown product of hemoglobin. Hemoglobin is first convereted to biliverdin then bilirubin. | ||
*[['''Pallor''']]: This occurs due to anemia and loss of oxygen-carrying ability of blood. Pallor can occur in the [[skin]] or [[mucous membrane]] . | *[['''Pallor''']]: This occurs due to anemia and loss of oxygen-carrying ability of blood. Pallor can occur in the [[skin]] or [[mucous membrane]] . | ||
*[[Splenomegaly]]: In the case of extravascular hemolysis, the spleen can be enlarged. The spleen is the site of destruction of the red blood cells. | *[['''Splenomegaly''']]: In the case of extravascular hemolysis, the spleen can be enlarged. The spleen is the site of destruction of the red blood cells. | ||
==References== | ==References== | ||
Revision as of 05:50, 17 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]
Overview
Physical Examination
The physical examination findings of hemolytic anemia reflect (1) red blood cell loss and (2) the release of hemoglobin and its breakdown productions into the circulation. Exam findings in hemolytic anemia include:
- '''Jaundice''': This is due to Increased serum bilirubin levels in blood. Bilirubin is a breakdown product of hemoglobin. Hemoglobin is first convereted to biliverdin then bilirubin.
- '''Pallor''': This occurs due to anemia and loss of oxygen-carrying ability of blood. Pallor can occur in the skin or mucous membrane .
- '''Splenomegaly''': In the case of extravascular hemolysis, the spleen can be enlarged. The spleen is the site of destruction of the red blood cells.