Hemolytic anemia epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Shyam Patel [2]

Overview

In general, hemolytic anemia is a relatively rare condition. The incidence and prevalence are fairly low.

Epidemiology and Demographics

  • Worldwide, the incidence of autoimmune hemolytic anemia is 0.8 per 100,000 persons.[1] Some studies suggest that the incidence of autoimmune hemolytic anemia in adults in 1:100,000 persons.[2] The incidence of hemolytic anemia is lower in children.
  • Worldwide, the prevalence of autoimmune hemolytic anemia is 17 per 100,000 persons.[1]
  • Worldwide, the incidence of drug-induced hemolytic anemia is 0.1 per 100,000 persons.[3]

Gender

  • Hemolytic anemia affects men and women equally.

Race

  • Hemolytic anemia affects all races equally.

Age

  • Hemolytic anemia affects adults more commonly than children.[2]

References

  1. 1.0 1.1 Baek SW, Lee MW, Ryu HW, Lee KS, Song IC, Lee HJ; et al. (2011). "Clinical features and outcomes of autoimmune hemolytic anemia: a retrospective analysis of 32 cases". Korean J Hematol. 46 (2): 111–7. doi:10.5045/kjh.2011.46.2.111. PMC 3128891. PMID 21747883.
  2. 2.0 2.1 Berentsen S, Sundic T (2015). "Red blood cell destruction in autoimmune hemolytic anemia: role of complement and potential new targets for therapy". Biomed Res Int. 2015: 363278. doi:10.1155/2015/363278. PMC 4326213. PMID 25705656.
  3. Packman CH (2015). "The Clinical Pictures of Autoimmune Hemolytic Anemia". Transfus Med Hemother. 42 (5): 317–24. doi:10.1159/000440656. PMC 4678314. PMID 26696800.

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