Hemolytic-uremic syndrome

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Hemolytic-uremic syndrome
ICD-10 D59.3
ICD-9 283.11
OMIM 235400
DiseasesDB 13052
MedlinePlus 000510
MeSH D006463

Hemolytic-uremic syndrome Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hemolytic-uremic syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Synonyms and keywords:

Overview

Classification

Pathophysiology

  • shiga toxin–induced

endothelial cytotoxicity in the hemolytic uremic syndrome after infection with shiga toxin–producing Escherichia coli or other microorganisms. Thrombotic microangiopathy can also occur in patients with pneumococcal sepsis and less commonly other infections in which microbial neuraminidases expose the Thomsen-Friedenreich antigen on endothelial and red cells, subjecting the cells to attack by preexisting antibodies against the antigen

Causes

Differentiating Hemolytic-uremic syndrome from other Diseases

Epidemiology and Demographics

Hemolytic uremic syndrome occurs one to three cases per 100,000 children in children one to 10 years of age annually.

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention |Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Related chapters

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