Hashimoto's thyroiditis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Laboratory Findings

Electrolyte and Biomarker Studies

  • Thyroid-stimulating hormone (TSH)
  • Free T3 and Free T4
  • Anti-thyroglobulin antibodies (anti-Tg)
  • Anti-thyroid peroxidase antibodies (anti-TPO)
  • Anti-microsomal antibodies can help obtain an accurate diagnosis.[1] Earlier assessment of the patient may present with elevated levels of thyroglobulin owing to the transient thyrotoxicosis as inflammation within the thyroid causes damage to the integrity of thyroid follicle storage of thyroglobulin; TSH is concomitantly decreased.[2]
  • Diagnosis is made by detecting elevated levels of Anti-TPO antibodies in the serum.

References

  1. Giannini, AJ (1986). The Biological Foundations of Clinical Psychiatry. New Hyde Park, NY: Medical Examination Publishing Company. pp. 193–198. ISBN 0-87488-449-7.
  2. Simmons, PJ (1998). "Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1beta and interleukin-6". Endocrinology. 139 (7): 3158–3186. doi:10.1210/en.139.7.3148. PMID 9645688. Unknown parameter |month= ignored (help); Unknown parameter |coauthors= ignored (help)