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{{Hamartoma}}
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==Overview==
==Overview==
Hamartomas may be classified into different types based on their location, such as: [[lung]] (most common), [[heart]], [[hypothalamus]], [[kidneys]], or [[spleen]]. Other classifications can consider lesion class, dividing hamartomas into 4 different categories, such as: bone-forming, cartilage-forming, fiber-forming, and benign non–matrix-forming.<ref name="kumar">Kumar V, Abbas AK, Aster JC. Robbins Basic Pathology. Elsevier Health Sciences; 2012.</ref>
Hamartomas may be classified into different types based on their location, such as [[lung]] (most common), [[heart]], [[hypothalamus]], [[kidneys]], or [[spleen]]. Other classification method considers lesion class, dividing [[hamartomas]] into 4 different categories, such as [[bone]]-forming, [[cartilage]]-forming, [[fiber]]-forming, and [[benign]] non–matrix-forming.


==Classification==
==Classification==
===Location===
===Location===
Based on the location, hamartomas can be classified into the following types:
Based on the location, [[hamartomas]] can be classified into the following types:<ref name="pmid7316862">{{cite journal |vauthors=Patterson HC, Dickerson GR, Pilch BZ, Bentkover SH |title=Hamartoma of the hypopharynx |journal=Arch Otolaryngol |volume=107 |issue=12 |pages=767–72 |date=December 1981 |pmid=7316862 |doi= |url=}}</ref><ref name="pmid11297501">{{cite journal |vauthors=Read RW, Burnstine M, Rowland JM, Zamir E, Rao NA |title=Rhabdomyomatous mesenchymal hamartoma of the eyelid: report of a case and literature review |journal=Ophthalmology |volume=108 |issue=4 |pages=798–804 |date=April 2001 |pmid=11297501 |doi= |url=}}</ref>
*[[Lung]]
{| class="wikitable"
**Endobronchial pulmonary hamartoma
|+
**Parenchymal pulmonary hamartoma
!Location
*[[Heart]]
!Type
**Rhabdomyoma
|-
*[[Hypothalamus]]
|[[CNS]]
**Hypothalamic hamartoma
|
*[[Kidneys]]
* [[Hypothalamic hamartoma]]
**Angiomyolipoma
*[[Spleen]]
**Splenic hamartoma


===Lesion class===
* [[Neurofibromatosis]] in [[von Recklinghausen disease]]
* Neuroepithelial cells in [[tuberous sclerosis]]
|-
|[[Hypopharynx]]
|
* Hypopharyngeal rhabdomyomatous
|-
|[[Eyelid]]
|
* [[Rhabdomyomatous mesenchymal hamartomas|Rhabdomyomatous mesenchymal hamartoma]]
|-
|[[Lung]]
|
* Endobronchial pulmonary [[hamartoma]]


Based on the lesion class, hamartomas can be classified into the following types:
* Parenchymal [[pulmonary]] [[hamartoma]]
* [[Bronchial]] [[hamartoma]]
|-
|[[Heart]]
|
* [[Rhabdomyoma]]
|-
|[[Bowel]]
|
* Peutz-Jeghers [[polyp]]
* [[Polyp]] of the large bowel
|-
|[[Kidneys]]
|
* [[Angiomyolipoma]]
|-
|[[Spleen]]
|
* [[Splenic]] [[hamartoma]]
|-
|Skin
|
*[[Melanocytic naevi|Melanocytic]] nevi
|}


* Bone-forming tumors
===Lesion class===
 
* Cartilage-forming tumors


* Fiber-forming tumors
Based on the lesion class, hamartomas may be classified into the following types:<ref name="kumar">Kumar V, Abbas AK, Aster JC. Robbins Basic Pathology. Elsevier Health Sciences; 2012.</ref>
**Nonossifying fibroma
**Fibrous dysplasia
**Mazabraud syndrome


* Benign non–matrix-forming tumors
{| class="wikitable"
|+
!Lesion class
!Tumors type
|-
|[[Cartilage]]-forming
|
* [[Enchondroma|Enchondromatosis]]
* [[Epiphyseal]] [[osteochondroma]]
* Multiple [[osteochondroma]]
* [[Osteochondroma]]
|-
|[[Fiber]]-forming
|
* [[Nonossifying fibroma]]
* [[Fibrous dysplasia]]
|-
|[[Bone]]-forming
|
* Osteopathia striata
* [[Melorheostosis]]
* [[Osteopoikilosis]]
* [[Bone island]]
|-
|[[Benign]] non-matrix-forming
|
* [[Skeletal]] hemangiomatosis
* [[Hemangioma]] of [[bone]]
|}
*


==References==
==References==

Latest revision as of 04:17, 5 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Vamsikrishna Gunnam M.B.B.S [3]

Overview

Hamartomas may be classified into different types based on their location, such as lung (most common), heart, hypothalamus, kidneys, or spleen. Other classification method considers lesion class, dividing hamartomas into 4 different categories, such as bone-forming, cartilage-forming, fiber-forming, and benign non–matrix-forming.

Classification

Location

Based on the location, hamartomas can be classified into the following types:[1][2]

Location Type
CNS
Hypopharynx
  • Hypopharyngeal rhabdomyomatous
Eyelid
Lung
Heart
Bowel
Kidneys
Spleen
Skin

Lesion class

Based on the lesion class, hamartomas may be classified into the following types:[3]

Lesion class Tumors type
Cartilage-forming
Fiber-forming
Bone-forming
Benign non-matrix-forming

References

  1. Patterson HC, Dickerson GR, Pilch BZ, Bentkover SH (December 1981). "Hamartoma of the hypopharynx". Arch Otolaryngol. 107 (12): 767–72. PMID 7316862.
  2. Read RW, Burnstine M, Rowland JM, Zamir E, Rao NA (April 2001). "Rhabdomyomatous mesenchymal hamartoma of the eyelid: report of a case and literature review". Ophthalmology. 108 (4): 798–804. PMID 11297501.
  3. Kumar V, Abbas AK, Aster JC. Robbins Basic Pathology. Elsevier Health Sciences; 2012.


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