Hamartoma classification: Difference between revisions

	Hamartoma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Hamartoma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
Staging
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Hamartoma classification On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Hamartoma classification All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Hamartoma classification
CDC on Hamartoma classification
Hamartoma classification in the news
Blogs on Hamartoma classification
Directions to Hospitals Treating Hamartoma
Risk calculators and risk factors for Hamartoma classification

VisualWikitext

Latest revision as of 04:17, 5 April 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Vamsikrishna Gunnam M.B.B.S [3]

Overview

Hamartomas may be classified into different types based on their location, such as lung (most common), heart, hypothalamus, kidneys, or spleen. Other classification method considers lesion class, dividing hamartomas into 4 different categories, such as bone-forming, cartilage-forming, fiber-forming, and benign non–matrix-forming.

Classification

Location

Based on the location, hamartomas can be classified into the following types:^[1]^[2]


Location	Type
CNS	Hypothalamic hamartoma Neurofibromatosis in von Recklinghausen disease Neuroepithelial cells in tuberous sclerosis
Hypopharynx	Hypopharyngeal rhabdomyomatous
Eyelid	Rhabdomyomatous mesenchymal hamartoma
Lung	Endobronchial pulmonary hamartoma Parenchymal pulmonary hamartoma Bronchial hamartoma
Heart	Rhabdomyoma
Bowel	Peutz-Jeghers polyp Polyp of the large bowel
Kidneys	Angiomyolipoma
Spleen	Splenic hamartoma
Skin	Melanocytic nevi

Lesion class

Based on the lesion class, hamartomas may be classified into the following types:^[3]


Lesion class	Tumors type
Cartilage-forming	Enchondromatosis Epiphyseal osteochondroma Multiple osteochondroma Osteochondroma
Fiber-forming	Nonossifying fibroma Fibrous dysplasia
Bone-forming	Osteopathia striata Melorheostosis Osteopoikilosis Bone island
Benign non-matrix-forming	Skeletal hemangiomatosis Hemangioma of bone

References

↑ Patterson HC, Dickerson GR, Pilch BZ, Bentkover SH (December 1981). "Hamartoma of the hypopharynx". Arch Otolaryngol. 107 (12): 767–72. PMID 7316862.
↑ Read RW, Burnstine M, Rowland JM, Zamir E, Rao NA (April 2001). "Rhabdomyomatous mesenchymal hamartoma of the eyelid: report of a case and literature review". Ophthalmology. 108 (4): 798–804. PMID 11297501.
↑ Kumar V, Abbas AK, Aster JC. Robbins Basic Pathology. Elsevier Health Sciences; 2012.

Template:WikiDoc Sources

[pmid7316862-1] Patterson HC, Dickerson GR, Pilch BZ, Bentkover SH (December 1981). "Hamartoma of the hypopharynx". Arch Otolaryngol. 107 (12): 767–72. PMID 7316862.

[pmid11297501-2] Read RW, Burnstine M, Rowland JM, Zamir E, Rao NA (April 2001). "Rhabdomyomatous mesenchymal hamartoma of the eyelid: report of a case and literature review". Ophthalmology. 108 (4): 798–804. PMID 11297501.

[kumar-3] Kumar V, Abbas AK, Aster JC. Robbins Basic Pathology. Elsevier Health Sciences; 2012.

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Hamartoma}}
-{{CMG}}{AE}}{{MV}}
+{{CMG}}{{AE}}{{MV}} {{VKG}}
 ==Overview==
+Hamartomas may be classified into different types based on their location, such as [[lung]] (most common), [[heart]], [[hypothalamus]], [[kidneys]], or [[spleen]]. Other classification method considers lesion class, dividing [[hamartomas]] into 4 different categories, such as [[bone]]-forming, [[cartilage]]-forming, [[fiber]]-forming, and [[benign]] non–matrix-forming.
-Hamartomas may be classified into subtypes based on their '''location''' and '''associated conditions'''.
 ==Classification==
+===Location===
+Based on the location, [[hamartomas]] can be classified into the following types:<ref name="pmid7316862">{{cite journal |vauthors=Patterson HC, Dickerson GR, Pilch BZ, Bentkover SH |title=Hamartoma of the hypopharynx |journal=Arch Otolaryngol |volume=107 |issue=12 |pages=767–72 |date=December 1981 |pmid=7316862 |doi= |url=}}</ref><ref name="pmid11297501">{{cite journal |vauthors=Read RW, Burnstine M, Rowland JM, Zamir E, Rao NA |title=Rhabdomyomatous mesenchymal hamartoma of the eyelid: report of a case and literature review |journal=Ophthalmology |volume=108 |issue=4 |pages=798–804 |date=April 2001 |pmid=11297501 |doi= |url=}}</ref>
+{| class="wikitable"
+|+
+!Location
+!Type
+|-
+|[[CNS]]
+|
+* [[Hypothalamic hamartoma]]
-Based on the genetic mutations, hereditary hamartomatous syndromes carry different gene mutations.
+* [[Neurofibromatosis]] in [[von Recklinghausen disease]]
+* Neuroepithelial cells in [[tuberous sclerosis]]
-===Familial inheritance===
+|-
+|[[Hypopharynx]]
-All the syndromes are inherited in the autosomal dominant manner and are conditioned by mutations in four genes, which are: BMPR1A, SMAD4, PTEN and STK11.
+|
+* Hypopharyngeal rhabdomyomatous
-* [[Juvenile polyposis syndrome]]
+|-
-* [[Peutz-Jeghers syndrome]]
+|[[Eyelid]]
-* Hereditary mixed polyposis syndrome
+|
-* PTEN hamartoma tumour syndrome
+* [[Rhabdomyomatous mesenchymal hamartomas|Rhabdomyomatous mesenchymal hamartoma]]
-* [[Cowden syndrome]]
+|-
-* Bannayan-Riley-Ruvalcaba syndrome
+|[[Lung]]
-* Proteus’es syndrome
+|
+* Endobronchial pulmonary [[hamartoma]]
-===Location===
-Based on the location, hamartomas can be classified into the following sub-types:
-'''* Bone-forming tumors'''
+* Parenchymal [[pulmonary]] [[hamartoma]]
+* [[Bronchial]] [[hamartoma]]
+|-
+|[[Heart]]
+|
+* [[Rhabdomyoma]]
+|-
+|[[Bowel]]
+|
+* Peutz-Jeghers [[polyp]]
+* [[Polyp]] of the large bowel
+|-
+|[[Kidneys]]
+|
+* [[Angiomyolipoma]]
+|-
+|[[Spleen]]
+|
+* [[Splenic]] [[hamartoma]]
+|-
+|Skin
+|
+*[[Melanocytic naevi|Melanocytic]] nevi
+|}
-'''* Cartilage-forming tumors'''
+===Lesion class===
-'''* '''Fiber-forming tumors'''
+Based on the lesion class, hamartomas may be classified into the following types:<ref name="kumar">Kumar V, Abbas AK, Aster JC. Robbins Basic Pathology. Elsevier Health Sciences; 2012.</ref>
-::Nonossifying fibroma
-::Fibrous dysplasia
-::Mazabraud syndrome
-'''* Benign non–matrix-forming tumors'''
+{| class="wikitable"
+|+
+!Lesion class
+!Tumors type
+|-
+|[[Cartilage]]-forming
+|
+* [[Enchondroma|Enchondromatosis]]
+* [[Epiphyseal]] [[osteochondroma]]
+* Multiple [[osteochondroma]]
+* [[Osteochondroma]]
+|-
+|[[Fiber]]-forming
+|
+* [[Nonossifying fibroma]]
+* [[Fibrous dysplasia]]
+|-
+|[[Bone]]-forming
+|
+* Osteopathia striata
+* [[Melorheostosis]]
+* [[Osteopoikilosis]]
+* [[Bone island]]
+|-
+|[[Benign]] non-matrix-forming
+|
+* [[Skeletal]] hemangiomatosis
+* [[Hemangioma]] of [[bone]]
+|}
+*
 ==References==
-{{reflist|2}}
+{{reflist|1}}
 [[Category:Disease]]
 [[Category:Types of cancer]]
-[[Category:Pulmonology]]
 {{WikiDoc Help Menu}}
 {{WikiDoc Sources}}
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Surgery]]