Goodpasture syndrome differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]

Overview

Goodpasture syndrome must be differentiated from other diseases that cause rapid progressive glomerulonephritis and pulmonary hemorrhage. ANCA associated vasculitis, are disorders that affect the renal and pulmonary system, must be differentiated from Goodpasture syndrome.[1]

Differential Diagnosis

Goodpasture syndrome must be differentiated from other diseases that cause rapid progressive glomerulonephritis and pulmonary hemorrhage. ANCA associated vasculitis, are disorders that affect the renal and pulmonary system, must be differentiated from Goodpasture syndrome.[2]

Differentiating Goodpasture syndrome from Other Diseases

Goodpasture syndrome must be differentiated from other diseases that cause rapid progressive glomerulonephritis and pulmonary hemorrhage, and include:[3]

  • Granulomatosis with polyangiitis
  • Eosinophilic granulomatosis with polyangiitis
  • Microscopic polyangiitis
  • Systemic lupus erythematosis
  • Henoch-Schonlein purpura
  • Microscopic polyarteritis

It is of extreme importance that Goodpasture syndrome be differentiated from Granulomatosis with polyangiitis as antineutrophil cytoplasmic antibodies can be seen in patients with Goodpasture syndrome.


References

  1. Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G; et al. (2015). "Goodpasture's syndrome: a clinical update". Autoimmun Rev. 14 (3): 246–53. doi:10.1016/j.autrev.2014.11.006. PMID 25462583.
  2. Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G; et al. (2015). "Goodpasture's syndrome: a clinical update". Autoimmun Rev. 14 (3): 246–53. doi:10.1016/j.autrev.2014.11.006. PMID 25462583.
  3. Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G; et al. (2015). "Goodpasture's syndrome: a clinical update". Autoimmun Rev. 14 (3): 246–53. doi:10.1016/j.autrev.2014.11.006. PMID 25462583.

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