Gestational trophoblastic neoplasia laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Increased quantitative [[human chorionic gonadotropin|beta HCG]] levels. | Increased quantitative [[human chorionic gonadotropin|beta HCG]] levels.<ref name=abc> Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015</ref> | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
'''Blood tests''' that may be done include:Website: <ref> Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015</ref> | '''Blood tests''' that may be done include:Website: <ref name=abc> Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015</ref> | ||
===Quantitative serum HCG=== | ===Quantitative serum HCG=== | ||
* [[Human chorionic gonadotropin]] (HCG or b-HCG) is the most common tumour marker test used to diagnose GTD. | * [[Human chorionic gonadotropin]] (HCG or b-HCG) is the most common tumour marker test used to diagnose GTD. | ||
Revision as of 15:31, 13 October 2015
Overview
Increased quantitative beta HCG levels.[1]
Laboratory Findings
Blood tests that may be done include:Website: [1]
Quantitative serum HCG
- Human chorionic gonadotropin (HCG or b-HCG) is the most common tumour marker test used to diagnose GTD.
- HCG is a very sensitive test for diagnosing most gestational trophoblastic tumours. HCG is usually measured in the blood, but it can also be measured in the urine.
- HCG levels are much higher in women with complete hydatidiform moles and gestational choriocarcinoma compared to HCG levels in women with a normal pregnancy.
- With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD.
- With placental site tumours, the HCG level may be slightly higher than normal, but it is not considered a good marker for this type of tumour.
- An HCG test can help find GTD after pregnancy or miscarriage as this hormone should not be present in the blood or urine soon afterward.
Human placental lactogen (hPL)
- Human placental lactogen (hPL) is a tumour marker that may be used to follow women with placental site trophoblastic tumours. High hPL levels are found in women with some types of GTD.
Complete blood count
- Complete blood count can check for anemia from long-term (chronic) vaginal bleeding.
Kidney function tests
Liver function tests
References
- ↑ 1.0 1.1 Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015