Gastroparesis other diagnostic studies: Difference between revisions

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=== Electrogastrography ===
=== Electrogastrography ===
* Electrogastrography is used to evaluate [[Stomach|gastric]] electrical activity.<ref name="pmid16457127">{{cite journal |vauthors=Rossi Z, Forlini G, Fenderico P, Cipolla R, Nasoni S |title=Electrogastrography |journal=Eur Rev Med Pharmacol Sci |volume=9 |issue=5 Suppl 1 |pages=29–35 |year=2005 |pmid=16457127 |doi= |url=}}</ref><ref>{{cite journal |vauthors=Sanmiguel CP, Mintchev MP, Bowes KL |title=Electrogastrography: a noninvasive technique to evaluate gastric electrical activity |journal=Can. J. Gastroenterol. |volume=12 |issue=6 |pages=423–30 |year=1998 |pmid=9784898 |doi= |url=}}</ref>
* Electrogastrography is used to evaluate [[Stomach|gastric]] electrical activity.<ref name="pmid16457127">{{cite journal |vauthors=Rossi Z, Forlini G, Fenderico P, Cipolla R, Nasoni S |title=Electrogastrography |journal=Eur Rev Med Pharmacol Sci |volume=9 |issue=5 Suppl 1 |pages=29–35 |year=2005 |pmid=16457127 |doi= |url=}}</ref><ref>{{cite journal |vauthors=Sanmiguel CP, Mintchev MP, Bowes KL |title=Electrogastrography: a noninvasive technique to evaluate gastric electrical activity |journal=Can. J. Gastroenterol. |volume=12 |issue=6 |pages=423–30 |year=1998 |pmid=9784898 |doi= |url=}}</ref>{{cite journal |vauthors=Schmoldt A, Benthe HF, Haberland G, Sinelnikova EM, Dvoretskova TV, Kagan ZS, Smith RC, Stricker CM, Bricot R, Parry WH, Martorano F, Cotton EK, Cheng HH, Führ F |title=Digitoxin metabolism by rat liver microsomes |journal=Biochem. Pharmacol. |volume=24 |issue=17 |pages=1639–41 |year=1975 |pmid=10 |doi= |url=}}
* Electrogastrography is useful for differentiating gastroparesis from [[Dyspepsia|functional dyspepsia]] by identifying underlying myoelectrical activity.
* Electrogastrography is useful for differentiating gastroparesis from [[Dyspepsia|functional dyspepsia]] by identifying underlying myoelectrical activity.
* In gastroparesis, motor patterns includes:
* In gastroparesis, motor patterns includes:
** Postprandial antral hypomotility due to infrequent contractions and/or low amplitudes
** Postprandial antral hypomotility due to infrequent contractions and/or low amplitudes
** abnormal propagation of antroduodenal contractions
** Abnormal propagation of antroduodenal contractions
** increased pyloric spasms which are characterized by an increased tonic and phasic activity
** Increased pyloric spasms which are characterized by an increased tonic and phasic activity
** abnormal migrating motor complexes (MMC), less frequently originating from the stomach
** Abnormal migrating motor complexes (MMC), less frequently originating from the stomach


==References==
==References==

Revision as of 19:00, 8 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]

Overview

Other diagnostic studies for diagnosis of gastroparesis include 13C-octanoic acid breath test, the SmartPill wireless motility capsule (WMC) system, and electrogastrography. All of them could measure the gastric motility and recognize delayed gastric emptying. Electrogastrography is useful for differentiating gastroparesis from functional dyspepsia by identifying underlying myoelectrical activity.

Other Diagnostic Studies

Breath Test

  • 13C-octanoic acid breath test may be helpful for diagnosis of gastroparesis. Features of breath test in diagnosis of gastroparesis include:[1][2][3]

The SmartPill wireless motility capsule (WMC) system 

  • The SmartPill is a small device in capsule form that can be swallowed and collects information from the gastrointestinal tract.[4]
  • It is used to evaluate suspected delayed emptying in gastroparesis and functional dyspepsia by measuring transit time in the stomach, small intestine, and colon.
  • It assess both regional and whole gut transit by measuring temperature, pH, and the pressure of its immediate surroundings.[5]

Electrogastrography

  • Electrogastrography is used to evaluate gastric electrical activity.[6][7]Schmoldt A, Benthe HF, Haberland G, Sinelnikova EM, Dvoretskova TV, Kagan ZS, Smith RC, Stricker CM, Bricot R, Parry WH, Martorano F, Cotton EK, Cheng HH, Führ F (1975). "Digitoxin metabolism by rat liver microsomes". Biochem. Pharmacol. 24 (17): 1639–41. PMID 10.
  • Electrogastrography is useful for differentiating gastroparesis from functional dyspepsia by identifying underlying myoelectrical activity.
  • In gastroparesis, motor patterns includes:
    • Postprandial antral hypomotility due to infrequent contractions and/or low amplitudes
    • Abnormal propagation of antroduodenal contractions
    • Increased pyloric spasms which are characterized by an increased tonic and phasic activity
    • Abnormal migrating motor complexes (MMC), less frequently originating from the stomach

References

  1. Zahn A, Langhans CD, Hoffner S, Haberkorn U, Rating D, Haass M, Enck P, Stremmel W, Rühl A (2003). "Measurement of gastric emptying by 13C-octanoic acid breath test versus scintigraphy in diabetics". Z Gastroenterol. 41 (5): 383–90. doi:10.1055/s-2003-39331. PMID 12772050.
  2. Tang, Derek M.; Friedenberg, Frank K. (2011). "Gastroparesis: Approach, Diagnostic Evaluation, and Management". Disease-a-Month. 57 (2): 74–101. doi:10.1016/j.disamonth.2010.12.007. ISSN 0011-5029.
  3. Koch, Kenneth L.; Calles-Escandón, Jorge (2015). "Diabetic Gastroparesis". Gastroenterology Clinics of North America. 44 (1): 39–57. doi:10.1016/j.gtc.2014.11.005. ISSN 0889-8553.
  4. Hasler WL (2014). "The use of SmartPill for gastric monitoring". Expert Rev Gastroenterol Hepatol. 8 (6): 587–600. doi:10.1586/17474124.2014.922869. PMID 24881810.
  5. Saad RJ (2016). "The Wireless Motility Capsule: a One-Stop Shop for the Evaluation of GI Motility Disorders". Curr Gastroenterol Rep. 18 (3): 14. doi:10.1007/s11894-016-0489-x. PMID 26908282.
  6. Rossi Z, Forlini G, Fenderico P, Cipolla R, Nasoni S (2005). "Electrogastrography". Eur Rev Med Pharmacol Sci. 9 (5 Suppl 1): 29–35. PMID 16457127.
  7. Sanmiguel CP, Mintchev MP, Bowes KL (1998). "Electrogastrography: a noninvasive technique to evaluate gastric electrical activity". Can. J. Gastroenterol. 12 (6): 423–30. PMID 9784898.

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